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Coagulopathy in COVID-19: Manifestations and management #MMPMID32409435
Mucha SR; Dugar S; McCrae K; Joseph D; Bartholomew J; Sacha GL; Militello M
Cleve Clin J Med 2020[Jul]; 87 (8): 461-468 PMID32409435show ga
Severe COVID-19 illness is associated with intense inflammation, leading to high rates of thrombotic complications that increase morbidity and mortality. Markedly elevated levels of D-dimer with normal fibrinogen levels are the hallmark laboratory findings of severe COVID-19- associated coagulopathy. Prophylaxis against venous thromboembolism is paramount for all hospitalized patients, with more aggressive prophylaxis and screening recommended for patients with D-dimer levels above 3.0 mug/mL. Point-of-care ultrasonography is the imaging method of choice for patients at high risk, as it entails minimal risk of exposing providers to the virus.