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10.3949/ccjm.87a.ccc009

http://scihub22266oqcxt.onion/10.3949/ccjm.87a.ccc009
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32409434!ä!32409434

suck abstract from ncbi

pmid32409434      Cleve+Clin+J+Med 2020 ; ä (ä): ä
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  • Renin-angiotensin system inhibitors in COVID-19 #MMPMID32409434
  • Thomas G
  • Cleve Clin J Med 2020[May]; ä (ä): ä PMID32409434show ga
  • Concerns have been raised about the potential for renin-angiotensin system (RAS) inhibitors to upregulate expression of angiotensin-converting enzyme 2 (ACE2) and thus increase susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry. Currently, there is no evidence that even if RAS inhibitors increase expression and activity of ACE2, that they would increase the risk of SARS-CoV-2 infection by facilitating greater viral entry or worsen outcomes in patients with COVID-19. At this time, there is no clinical evidence to suggest that treatment with RAS inhibitors should be discontinued in stable patients with COVID-19. In hospitalized patients with severe COVID-19, decisions about these medications should be based on clinical condition, including hemodynamic status and renal function.
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