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10.1002/cpt.1891 http://scihub22266oqcxt.onion/10.1002/cpt.1891 32407539!7272975!32407539     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Pharmacol+Ther 2020 ; 108 (4): 730-733 Nephropedia Template TP {{tp|p=32407539|t=2020. Clinical Trials for COVID-19: Can we Better Use the Short Window of Opportunity?|pdf=|usr=}}{{32407539}} gab.com Text Clinical Trials for COVID-19: Can we Better Use the Short Window of Opportunity JO: Clin Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=32407539 #FOAvip The scientific community has risen to the coronavirus disease 2019 (COVID-19) challenge, coming up with an impressive list of candidate drugs and vaccines targeting an array of pharmacological and immunological mechanisms. Yet, generating clinical evidence of efficacy and safety of these candidate treatments may be frustrated by the absence of comprehensive trial coordination mechanisms. Many small stand-alone trials and observational studies of single-agent interventions are currently running or in planning; many of these will likely not deliver robust results that could support regulatory and patient-level treatment decisions. In this paper, we discuss actions that all stakeholders in the clinical trial ecosystem need to take to ensure that the window of opportunity during this pandemic will not shut, both for patients in need of treatment and for researchers to conduct decision-relevant clinical trials. Twit Text FOAVip Clinical Trials for COVID-19: Can we Better Use the Short Window of Opportunity ????Clin Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=32407539 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32407539 #FOAvip English Wikipedia <ref>{{Cite pmid|32407539}}</ref> Clinical Trials for COVID-19: Can we Better Use the Short Window of Opportunity? #MMPMID32407539 Eichler HG; Cavaleri M; Enzmann H; Scotti F; Sepodes B; Sweeney F; Vamvakas S; Rasi G Clin Pharmacol Ther 2020[Oct]; 108 (4): 730-733 PMID32407539show ga The scientific community has risen to the coronavirus disease 2019 (COVID-19) challenge, coming up with an impressive list of candidate drugs and vaccines targeting an array of pharmacological and immunological mechanisms. Yet, generating clinical evidence of efficacy and safety of these candidate treatments may be frustrated by the absence of comprehensive trial coordination mechanisms. Many small stand-alone trials and observational studies of single-agent interventions are currently running or in planning; many of these will likely not deliver robust results that could support regulatory and patient-level treatment decisions. In this paper, we discuss actions that all stakeholders in the clinical trial ecosystem need to take to ensure that the window of opportunity during this pandemic will not shut, both for patients in need of treatment and for researchers to conduct decision-relevant clinical trials. |*Betacoronavirus[MESH] |Academic Medical Centers/methods/trends[MESH] |Biomedical Research/*methods/trends[MESH] |COVID-19[MESH] |Clinical Trials as Topic/*methods[MESH] |Coronavirus Infections/epidemiology/*therapy[MESH] |Drug Industry/methods/trends[MESH] |Drug and Narcotic Control/trends[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/epidemiology/*therapy[MESH] |SARS-CoV-2[MESH]Clinical Trials for COVID-19: Can we Better Use the Short Window of Op(epmc).pdf DeepDyve Pubget Overpricing