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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Minerva+Med 2020 ; 111 (4): 362-364 Nephropedia Template TP
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Hyper-immune/convalescent plasma: an old option and a valid strategy for treatment of COVID-19? #MMPMID32407051
Saverino D
Minerva Med 2020[Aug]; 111 (4): 362-364 PMID32407051show ga
Currently, there are no approved specific antiviral agents for novel coronavirus disease (COVID-19). Hyper-immune/convalescent plasma derived from recently recovered donors seems to be useful to treat COVID-19 patients, an addition to maximal supportive care and antiviral agents. The endpoints are the improvement of clinical symptoms and laboratory parameters of these patients. However, the efficacy of hyper-immune/convalescent plasma treatment for severe infectious diseases is still controversial. The optimal dose and time point, as well as the clinical benefit of hyper-immune/convalescent plasma therapy, needs further investigation in larger well-controlled trials.