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10.1128/mSphere.00317-20 http://scihub22266oqcxt.onion/10.1128/mSphere.00317-20 32404514!7227770!32404514     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       mSphere 2020 ; 5 (3): ä Nephropedia Template TP {{tp|p=32404514|t=2020. COVID-19: Learning from Lessons To Guide Treatment and Prevention Interventions |pdf=|usr=}}{{32404514}} gab.com Text COVID-19: Learning from Lessons To Guide Treatment and Prevention Interventions JO: mSphere http://www.kidney.de/pget.php?&tw=1&pmid=32404514 #FOAvip Coronavirus disease 2019 (COVID-19) is caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and first emerged in December 2019 in Wuhan, Hubei province, China. Since then, the virus has rapidly spread to many countries. While the outbreak in China appears to be in decline, the disease has spread across the world, with a daily increase in the number of confirmed cases and infection-related deaths. Here, we highlight (i) the lessons that have been learnt so far and how they will benefit reducing the impact of COVID-19 disease and (ii) an update on the status of drug treatment and vaccine development to prevent COVID-19 and potential future related pandemics. Although the mortality rate is clearly higher than for influenza, the rate does seem to vary from country to country, possibly reflecting differences in how rapidly local health authorities respond to isolate and effectively care for the affected population. Drugs are urgently needed for both prophylaxis and the treatment of severely ill patients; however, no proven effective therapies for SARS-CoV-2 currently exist. A number of drugs that have been approved for other diseases are being tested for the treatment of COVID-19 patients, but there is an absence of data from appropriately designed clinical trials showing that these drugs, either alone or in combination, will prove effective. There is also a global urgency to develop a vaccine against COVID-19, but development and appropriate testing will take at least a year before such a vaccine will be globally available. This review summarizes the lessons learnt so far from the COVID-19 pandemic, examines the evidence regarding the drugs that are being tested for the treatment of COVID19, and describes the progress made in efforts to develop an effective vaccine. Twit Text FOAVip COVID-19: Learning from Lessons To Guide Treatment and Prevention Interventions ????mSphere http://www.kidney.de/pget.php?&tw=1&pmid=32404514 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32404514 #FOAvip English Wikipedia <ref>{{Cite pmid|32404514}}</ref> COVID-19: Learning from Lessons To Guide Treatment and Prevention Interventions #MMPMID32404514 Triggle CR; Bansal D; Farag EABA; Ding H; Sultan AA mSphere 2020[May]; 5 (3): ä PMID32404514show ga Coronavirus disease 2019 (COVID-19) is caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and first emerged in December 2019 in Wuhan, Hubei province, China. Since then, the virus has rapidly spread to many countries. While the outbreak in China appears to be in decline, the disease has spread across the world, with a daily increase in the number of confirmed cases and infection-related deaths. Here, we highlight (i) the lessons that have been learnt so far and how they will benefit reducing the impact of COVID-19 disease and (ii) an update on the status of drug treatment and vaccine development to prevent COVID-19 and potential future related pandemics. Although the mortality rate is clearly higher than for influenza, the rate does seem to vary from country to country, possibly reflecting differences in how rapidly local health authorities respond to isolate and effectively care for the affected population. Drugs are urgently needed for both prophylaxis and the treatment of severely ill patients; however, no proven effective therapies for SARS-CoV-2 currently exist. A number of drugs that have been approved for other diseases are being tested for the treatment of COVID-19 patients, but there is an absence of data from appropriately designed clinical trials showing that these drugs, either alone or in combination, will prove effective. There is also a global urgency to develop a vaccine against COVID-19, but development and appropriate testing will take at least a year before such a vaccine will be globally available. This review summarizes the lessons learnt so far from the COVID-19 pandemic, examines the evidence regarding the drugs that are being tested for the treatment of COVID19, and describes the progress made in efforts to develop an effective vaccine. |Betacoronavirus[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19 Vaccines[MESH] |Communicable Disease Control/methods[MESH] |Coronavirus Infections/*drug therapy/epidemiology/*prevention & control[MESH] |Humans[MESH] |Pandemics/*prevention & control[MESH] |Pneumonia, Viral/*drug therapy/epidemiology/*prevention & control[MESH] |SARS-CoV-2[MESH]COVID-19: Learning from Lessons To Guide Treatment and Prevention Inte(epmc).pdf DeepDyve Pubget Overpricing