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10.1182/blood.2020006582

http://scihub22266oqcxt.onion/10.1182/blood.2020006582
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32403134!7316219!32403134
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suck abstract from ncbi


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pmid32403134      Blood 2020 ; 135 (25): 2320-2322
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  • Combination dose-escalated hydroxyurea and transfusion: an approach to conserve blood during the COVID-19 pandemic #MMPMID32403134
  • Nickel RS; Margulies S; Frazer B; Luban NLC; Webb J
  • Blood 2020[Jun]; 135 (25): 2320-2322 PMID32403134show ga
  • Nickel et al describe a single-arm trial using dose-escalated hydroxyurea and regular transfusions to prevent complications of sickle cell anemia. Preliminary results suggest that a reduction in volume of red cell requirements may be achievable.
  • |*Blood Transfusion/statistics & numerical data[MESH]
  • |*Coronavirus Infections[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Anemia, Sickle Cell/complications/drug therapy/*therapy[MESH]
  • |Blood Donors/supply & distribution[MESH]
  • |Blood Safety[MESH]
  • |COVID-19[MESH]
  • |Chelation Therapy[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Combined Modality Therapy[MESH]
  • |Dose-Response Relationship, Drug[MESH]
  • |Drug Monitoring[MESH]
  • |Humans[MESH]
  • |Hydroxyurea/*administration & dosage/adverse effects/therapeutic use[MESH]
  • |Risk[MESH]
  • |Secondary Prevention/methods[MESH]
  • |Social Isolation[MESH]
  • |Stroke/prevention & control[MESH]
  • |Telemedicine[MESH]


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