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10.1016/j.jcv.2020.104417 http://scihub22266oqcxt.onion/10.1016/j.jcv.2020.104417 32403007!7198188!32403007     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Virol 2020 ; 128 (ä): 104417 Nephropedia Template TP {{tp|p=32403007|t=2020. Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic |pdf=|usr=}}{{32403007}} gab.com Text Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic JO: J Clin Virol http://www.kidney.de/pget.php?&tw=1&pmid=32403007 #FOAvip OBJECTIVES: To evaluate the reliability of self-collection for SARS-CoV-2 and other respiratory viruses because swab collections for SARS-CoV-2 put health workers at risk of infection and require use of personal protective equipment (PPE). METHODS: In a prospective study, patients from two states in Australia attending dedicated COVID-19 collection clinics were offered the option to first self-collect (SC) nasal and throat swabs (SCNT) prior to health worker collect (HC) using throat and nasal swabs (Site 1) or throat and nasopharyngeal swabs (Site 2). Samples were analysed for SARS-CoV-2 as well as common respiratory viruses. Concordance of results between methods was assessed using Cohen's kappa (kappa) and Cycle threshold (Ct) values were recorded for all positive results as a surrogate measure for viral load. RESULTS: Of 236 patients sampled by HC and SC, 25 had SARS-CoV-2 (24 by HC and 25 by SC) and 63 had other respiratory viruses (56 by HC and 58 by SC). SC was highly concordant with HC (kappa?=?0.890) for all viruses including SARS-CoV-2 and more concordant than HC to positive results by any method (kappa?=?0.959 vs 0.933). Mean SARS-CoV-2 E-gene and N-gene, rhinovirus and parainfluenza Ct values did not differ between HC and SCNT. CONCLUSIONS: Self-collection of nasal and throat swabs offers a reliable alternative to health worker collection for the diagnosis of SARS-CoV-2 and other respiratory viruses and provides patients with easier access to testing, reduces exposure of the community and health workers to those being tested and reduces requirement for PPE. Twit Text FOAVip Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic ????J Clin Virol http://www.kidney.de/pget.php?&tw=1&pmid=32403007 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32403007 #FOAvip English Wikipedia <ref>{{Cite pmid|32403007}}</ref> Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic #MMPMID32403007 Wehrhahn MC; Robson J; Brown S; Bursle E; Byrne S; New D; Chong S; Newcombe JP; Siversten T; Hadlow N J Clin Virol 2020[Jul]; 128 (ä): 104417 PMID32403007show ga OBJECTIVES: To evaluate the reliability of self-collection for SARS-CoV-2 and other respiratory viruses because swab collections for SARS-CoV-2 put health workers at risk of infection and require use of personal protective equipment (PPE). METHODS: In a prospective study, patients from two states in Australia attending dedicated COVID-19 collection clinics were offered the option to first self-collect (SC) nasal and throat swabs (SCNT) prior to health worker collect (HC) using throat and nasal swabs (Site 1) or throat and nasopharyngeal swabs (Site 2). Samples were analysed for SARS-CoV-2 as well as common respiratory viruses. Concordance of results between methods was assessed using Cohen's kappa (kappa) and Cycle threshold (Ct) values were recorded for all positive results as a surrogate measure for viral load. RESULTS: Of 236 patients sampled by HC and SC, 25 had SARS-CoV-2 (24 by HC and 25 by SC) and 63 had other respiratory viruses (56 by HC and 58 by SC). SC was highly concordant with HC (kappa?=?0.890) for all viruses including SARS-CoV-2 and more concordant than HC to positive results by any method (kappa?=?0.959 vs 0.933). Mean SARS-CoV-2 E-gene and N-gene, rhinovirus and parainfluenza Ct values did not differ between HC and SCNT. CONCLUSIONS: Self-collection of nasal and throat swabs offers a reliable alternative to health worker collection for the diagnosis of SARS-CoV-2 and other respiratory viruses and provides patients with easier access to testing, reduces exposure of the community and health workers to those being tested and reduces requirement for PPE. |*Pandemics[MESH] |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Australia[MESH] |Betacoronavirus/*isolation & purification[MESH] |COVID-19[MESH] |Child[MESH] |Coronavirus Infections/*diagnosis/virology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Nasopharynx/virology[MESH] |Nose/virology[MESH] |Pharynx/virology[MESH] |Pneumonia, Viral/*diagnosis/virology[MESH] |Prospective Studies[MESH] |Reproducibility of Results[MESH] |SARS-CoV-2[MESH] |Specimen Handling/*methods[MESH] |Viral Load[MESH]Self-collection: An appropriate alternative during the SARS-CoV-2 pand(epmc).pdf DeepDyve Pubget Overpricing