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10.1016/j.ceca.2020.102212

http://scihub22266oqcxt.onion/10.1016/j.ceca.2020.102212
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32402856!7201244!32402856
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suck abstract from ncbi


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pmid32402856      Cell+Calcium 2020 ; 88 (ä): 102212
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  • Could an endo-lysosomal ion channel be the Achilles heel of SARS-CoV2? #MMPMID32402856
  • Grimm C; Tang R
  • Cell Calcium 2020[Jun]; 88 (ä): 102212 PMID32402856show ga
  • The ongoing SARS-CoV2 outbreak has developed into a global pandemic. Despite previous outbreaks of SARS-CoV and the related MERS-CoV in recent years, neither a vaccine nor any other medication for an effective treatment are currently available. Endo-lysosomal two-pore cation channels have now emerged as potential novel targets for SARS-CoV treatment.
  • |Animals[MESH]
  • |Betacoronavirus/drug effects/*metabolism[MESH]
  • |COVID-19[MESH]
  • |Calcium Channel Blockers/pharmacology/therapeutic use[MESH]
  • |Calcium Channels/metabolism[MESH]
  • |Coronavirus Infections/drug therapy/*metabolism[MESH]
  • |Humans[MESH]
  • |Ion Channels/*antagonists & inhibitors/*metabolism[MESH]
  • |Lysosomes/drug effects/*metabolism[MESH]
  • |Middle East Respiratory Syndrome Coronavirus/drug effects/metabolism[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/drug therapy/*metabolism[MESH]
  • |Protein Transport/drug effects/physiology[MESH]
  • |SARS-CoV-2[MESH]


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