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Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection #MMPMID32400380
Troldborg A; Bartels LE; Deleuran B
Ugeskr Laeger 2020[May]; 182 (20): ä PMID32400380show ga
The severity of COVID-19 disease has led to an urgent need for the discovery of new treatments. Thus, global stocks of hydroxychloroquine (HCQ) have been put under pressure with a study of 26 patients treated with HCQ during their infection with SARS-CoV-2. Despite the study's lack of quality, several countries' medicines agencies subsequently issued guidelines for the use of HCQ for COVID-19. This review aims to elucidate potential mechanisms, which make HCQ treatment interesting in the fight against SARS-CoV-2 infection, as well as the current evidence for clinical use of HCQ to treat COVID-19.