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10.1007/s15010-020-01438-z

http://scihub22266oqcxt.onion/10.1007/s15010-020-01438-z
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32394344!7211976!32394344
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suck abstract from ncbi


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pmid32394344      Infection 2020 ; 48 (5): 681-686
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  • COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients #MMPMID32394344
  • Harter G; Spinner CD; Roider J; Bickel M; Krznaric I; Grunwald S; Schabaz F; Gillor D; Postel N; Mueller MC; Muller M; Romer K; Schewe K; Hoffmann C
  • Infection 2020[Oct]; 48 (5): 681-686 PMID32394344show ga
  • INTRODUCTION: Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population. METHODS: Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome. RESULTS: Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir. CONCLUSIONS: This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART.
  • |Adult[MESH]
  • |Antiretroviral Therapy, Highly Active[MESH]
  • |Betacoronavirus/drug effects/immunology/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |Coinfection[MESH]
  • |Coronavirus Infections/drug therapy/mortality/pathology/*virology[MESH]
  • |Darunavir/*therapeutic use[MESH]
  • |Female[MESH]
  • |HIV Infections/drug therapy/mortality/pathology/*virology[MESH]
  • |HIV/drug effects/immunology/*pathogenicity[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/drug therapy/mortality/pathology/*virology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Survival Analysis[MESH]
  • |Tenofovir/*therapeutic use[MESH]


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