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  • Coronavirus Disease 2019 and the Cerebrovascular-Cardiovascular Systems: What Do We Know So Far? #MMPMID32393136
  • Larson AS; Savastano L; Kadirvel R; Kallmes DF; Hassan AE; Brinjikji W
  • J Am Heart Assoc 2020[Jul]; 9 (13): e016793 PMID32393136show ga
  • The severe acute respiratory syndrome coronavirus 2 pandemic of 2019 to 2020 has resulted in multiple hospitalizations, deaths, and economic hardships worldwide. Although respiratory involvement in patients with coronavirus disease 2019 (COVID-19) is well known, the potential cardiovascular and cerebrovascular manifestations are less understood. We performed a PubMed and Google Scholar search and reviewed relevant literature on COVID-19 and cardiovascular system involvement. Severe acute respiratory syndrome coronavirus 2 possesses high affinity for angiotensin-converting enzyme 2 receptor, which is highly concentrated in the lungs and cardiovascular tissue, thereby provoking concern for cardiovascular involvement in COVID-19 cases. Preexisting cardiovascular and cerebrovascular disease has been shown in previous reports to be a risk factor for severe infection. On the basis of our review of published studies, COVID-19 patients may be more likely to experience acute cardiac injury, arrhythmia, coagulation defects, and acute stroke and are likely to have poorer outcomes as a result. As the COVID-19 pandemic continues, more data about potential cardiovascular and cerebrovascular manifestations of the disease are required.
  • |*Betacoronavirus[MESH]
  • |*Pandemics[MESH]
  • |Cardiovascular Diseases/*epidemiology[MESH]
  • |Cerebrovascular Disorders/*epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*epidemiology[MESH]
  • |Global Health[MESH]
  • |Humans[MESH]
  • |Pneumonia, Viral/*epidemiology[MESH]
  • |Risk Factors[MESH]

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  • suck abstract from ncbi

    e016793 13.9 2020