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Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Clin+Infect+Dis 2020 ; 71 (16): 2187-2190 Nephropedia Template TP
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Coronavirus Disease 2019 (COVID-19) Clinical Trial Oversight at a Major Academic Medical Center: Approach of Michigan Medicine #MMPMID32392334
Spector-Bagdady K; Higgins PDR; Aaronson KD; Birk J; Flaherty KR; Gregg KS; Hyzy RC; Kaul DR; Lauring AS; Magee JC; Meurer WJ; Park PK; Scott P; Lok AS
Clin Infect Dis 2020[Nov]; 71 (16): 2187-2190 PMID32392334show ga
Clinicians, eager to offer the best care in the absence of guiding data, have provided patients with coronavirus disease 2019 (COVID-19) diverse clinical interventions. This usage has led to perceptions of efficacy of some interventions that, while receiving media coverage, lack robust evidence. Moving forward, randomized controlled clinical trials are necessary to ensure that clinicians can treat patients effectively during this outbreak and the next. To do so, academic medical centers must address 2 key research issues: (1) how to effectively and efficiently determine which trials have the best chance of benefiting current and future patients and (2) how to establish a transparent and ethical process for subject recruitment while maintaining research integrity and without overburdening patients or staff. We share here the current methods used by Michigan Medicine to address these issues.
|*Academic Medical Centers[MESH]
|COVID-19/*therapy[MESH]
|Humans[MESH]
|Informed Consent[MESH]
|Michigan[MESH]
|Patient Selection/*ethics[MESH]
|Randomized Controlled Trials as Topic/*standards[MESH]