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10.1093/cid/ciaa557 http://scihub22266oqcxt.onion/10.1093/cid/ciaa557 32392331!7239243!32392331     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Infect+Dis 2020 ; 71 (16): 2099-2108 Nephropedia Template TP {{tp|p=32392331|t=2020. Household Transmission of SARS-CoV-2, Zhuhai, China, 2020 |pdf=|usr=}}{{32392331}} gab.com Text Household Transmission of SARS-CoV-2, Zhuhai, China, 2020 JO: Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32392331 #FOAvip BACKGROUND: To illustrate the extent of transmission, identify affecting risk factors and estimate epidemiological modeling parameters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in household setting. METHODS: We enrolled 35 confirmed index cases and their 148 household contacts, January 2020-February 2020, in Zhuhai, China. All participants were interviewed and asked to complete questionnaires. Household contacts were then prospectively followed active symptom monitoring through the 21-day period and nasopharyngeal and/or oropharyngeal swabs were collected at 3-7 days intervals. Epidemiological, demographic, and clinical data (when available) were collected. RESULTS: Assuming that all these secondary cases were infected by their index cases, the second infection rate in household context is 32.4% (95% confidence interval [CI]: 22.4%-44.4%), with 10.4% of secondary cases being asymptomatic. Multivariate analysis showed that household contacts with underlying medical conditions, a history of direct exposure to Wuhan and its surrounding areas, and shared vehicle with an index patient were associated with higher susceptibility. Household members without protective measures after illness onset of the index patient seem to increase the risk for SARS-CoV-2 infection. The median incubation period and serial interval within household were estimated to be 4.3 days (95% CI: 3.4-5.3 days) and 5.1 days (95% CI: 4.3-6.2 days), respectively. CONCLUSION: Early isolation of patients with coronavirus disease 2019 and prioritizing rapid contact investigation, followed by active symptom monitoring and periodic laboratory evaluation, should be initiated immediately after confirming patients to address the underlying determinants driving the continuing pandemic. Twit Text FOAVip Household Transmission of SARS-CoV-2, Zhuhai, China, 2020 ????Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32392331 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32392331 #FOAvip English Wikipedia <ref>{{Cite pmid|32392331}}</ref> Household Transmission of SARS-CoV-2, Zhuhai, China, 2020 #MMPMID32392331 Wu J; Huang Y; Tu C; Bi C; Chen Z; Luo L; Huang M; Chen M; Tan C; Wang Z; Wang K; Liang Y; Huang J; Zheng X; Liu J Clin Infect Dis 2020[Nov]; 71 (16): 2099-2108 PMID32392331show ga BACKGROUND: To illustrate the extent of transmission, identify affecting risk factors and estimate epidemiological modeling parameters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in household setting. METHODS: We enrolled 35 confirmed index cases and their 148 household contacts, January 2020-February 2020, in Zhuhai, China. All participants were interviewed and asked to complete questionnaires. Household contacts were then prospectively followed active symptom monitoring through the 21-day period and nasopharyngeal and/or oropharyngeal swabs were collected at 3-7 days intervals. Epidemiological, demographic, and clinical data (when available) were collected. RESULTS: Assuming that all these secondary cases were infected by their index cases, the second infection rate in household context is 32.4% (95% confidence interval [CI]: 22.4%-44.4%), with 10.4% of secondary cases being asymptomatic. Multivariate analysis showed that household contacts with underlying medical conditions, a history of direct exposure to Wuhan and its surrounding areas, and shared vehicle with an index patient were associated with higher susceptibility. Household members without protective measures after illness onset of the index patient seem to increase the risk for SARS-CoV-2 infection. The median incubation period and serial interval within household were estimated to be 4.3 days (95% CI: 3.4-5.3 days) and 5.1 days (95% CI: 4.3-6.2 days), respectively. CONCLUSION: Early isolation of patients with coronavirus disease 2019 and prioritizing rapid contact investigation, followed by active symptom monitoring and periodic laboratory evaluation, should be initiated immediately after confirming patients to address the underlying determinants driving the continuing pandemic. |Adolescent[MESH] |Adult[MESH] |COVID-19/*transmission[MESH] |China/epidemiology[MESH] |Confidence Intervals[MESH] |Female[MESH] |Humans[MESH] |Infectious Disease Incubation Period[MESH] |Male[MESH] |Middle Aged[MESH] |Multivariate Analysis[MESH] |SARS-CoV-2/*pathogenicity[MESH]Household Transmission of SARS-CoV-2, Zhuhai, China, 2020 (epmc).pdf DeepDyve Pubget Overpricing