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suck abstract from ncbi

pmid32391999      Ned+Tijdschr+Geneeskd 2020 ; 164 (?): ?
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  • Chloroquine als mogelijke behandeling van COVID-19 #MMPMID32391999
  • Coumou J; de Vries PJ
  • Ned Tijdschr Geneeskd 2020[Mar]; 164 (?): ? PMID32391999show ga
  • Since the outbreak of COVID-19, chloroquine has been mentioned as a possible treatment. In vitro studies have shown anti-viral activity of chloroquine against SARS-CoV-2. Recently, the Dutch National Institute for Public Health and the Environment published treatment options for antiviral treatment for COVID-19 where chloroquine was suggested as first choice for off-label treatment, beside remdesivir en lopinavir/ritonavir. In this commentary, we provide a background and history of chloroquine, the evidence for antiviral efficacy of chloroquine and the arguments for off-label use of chloroquine in COVID-19.
  • |*Betacoronavirus[MESH]
  • |Adenosine Monophosphate/analogs & derivatives/therapeutic use[MESH]
  • |Alanine/analogs & derivatives/therapeutic use[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |COVID-19[MESH]
  • |Chloroquine/*therapeutic use[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Humans[MESH]
  • |Lopinavir/therapeutic use[MESH]
  • |Off-Label Use[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]
  • |Ritonavir/therapeutic use[MESH]
  • |SARS-CoV-2[MESH]


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