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10.1016/j.jinf.2020.04.033

http://scihub22266oqcxt.onion/10.1016/j.jinf.2020.04.033
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suck abstract from ncbi


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pmid32389784      J+Infect 2020 ; 81 (2): e6-e10
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  • Dynamic profile for the detection of anti-SARS-CoV-2 antibodies using four immunochromatographic assays #MMPMID32389784
  • Demey B; Daher N; Francois C; Lanoix JP; Duverlie G; Castelain S; Brochot E
  • J Infect 2020[Aug]; 81 (2): e6-e10 PMID32389784show ga
  • In order to fight the SARS-CoV-2 pandemic infection, there is a growing need and demand for diagnostic tools that are complementary and different from the RT-PCR currently in use. Multiple serological tests are or will be very soon available but need to be evaluated and validated. We have thus tested 4 immunochromatographic tests for the detection of antibodies to SARS-CoV-2. In addition, we assessed the kinetics of antibody appearance using these assays in 22 patients after they were tested positive by RT-PCR. We observed great heterogeneity in antibody detection post-symptom onset. The median antibody detection time was between 8 and 10 days according to the manufacturers. All the tests showed a sensitivity of 60 to 80% on day 10 and 100% on day 15. In addition, a single cross-reaction was observed with other human coronavirus infections. Thus, immunochromatographic tests for the detection of anti-SARS-CoV-2 antibodies may have their place for the diagnostic panel of COVID-19.
  • |Antibodies, Viral/*analysis/immunology[MESH]
  • |Betacoronavirus/*immunology[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Clinical Laboratory Techniques/*methods[MESH]
  • |Coronavirus Infections/*diagnosis/ethnology/immunology[MESH]
  • |Humans[MESH]
  • |Immunoassay/*methods[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/immunology[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]


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