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10.1016/j.dsx.2020.04.045

http://scihub22266oqcxt.onion/10.1016/j.dsx.2020.04.045
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suck abstract from ncbi


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pmid32388332      Diabetes+Metab+Syndr 2020 ; 14 (4): 519-520
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  • SARS-CoV-2 infection and glucose homeostasis in pregnancy What about antenatal corticosteroids? #MMPMID32388332
  • Kakoulidis I; Ilias I; Koukkou E
  • Diabetes Metab Syndr 2020[Jul]; 14 (4): 519-520 PMID32388332show ga
  • BACKGROUND AND AIMS: Administration of corticosteroids is common in obstetric practice. In this concise review we queried on the effects of corticosteroids in pregnancies complicated by SARS-CoV-2. METHODS: We performed a literature search on PubMed, regarding the use of corticosteroids in patients with SARS-CoV-2 infection, in pregnancies complicated by SARS-CoV-2, as well as their impact on glycemia in pregnant women with or without diabetes. Furthermore, we searched for effects of SARS-CoV-2 and of other coronaviridae on insulin secretion and glycemia. RESULTS: SARS-CoV-2 infection appears to be a risk factor for complications in pregnancy. Corticosteroids may not be recommended for treating SARS-CoV-2 pneumonia but they may be needed for at-risk pregnancies. Corticosteroids in pregnancy have a diabetogenic potential. SARS-CoV-2 and other coronaviridae may have effects on glycemia. CONCLUSIONS: Caution should be exercised while using corticosteroids in pregnant women with COVID-19 requiring preterm delivery.
  • |Adrenal Cortex Hormones/*pharmacology[MESH]
  • |Betacoronavirus/drug effects/pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/*complications/drug therapy/virology[MESH]
  • |Diabetes Mellitus/*physiopathology[MESH]
  • |Female[MESH]
  • |Homeostasis[MESH]
  • |Humans[MESH]
  • |Hyperglycemia/etiology/metabolism/*pathology[MESH]
  • |Hypoglycemia/etiology/metabolism/*pathology[MESH]
  • |Insulin Secretion/drug effects[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/drug therapy/virology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/etiology/metabolism/*pathology[MESH]


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