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10.1016/j.dsx.2020.04.033

http://scihub22266oqcxt.onion/10.1016/j.dsx.2020.04.033
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32387864!7189186!32387864
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suck abstract from ncbi


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pmid32387864      Diabetes+Metab+Syndr 2020 ; 14 (4): 469-471
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  • SARS-CoV-2 infection and obesity: Common inflammatory and metabolic aspects #MMPMID32387864
  • Michalakis K; Ilias I
  • Diabetes Metab Syndr 2020[Jul]; 14 (4): 469-471 PMID32387864show ga
  • BACKROUND AND AIMS: According to the World Obesity Federation, "obesity-related conditions seem to worsen the effect of Covid-19 (SARS-CoV-2)"; additionally the Centres for Disease Control and Prevention reported that "people with heart disease and diabetes are at higher risk of SARS-CoV-2 complications and that severe obesity poses a higher risk for severe illness". Recent reports have shown elevated levels of cytokines due to increased inflammation in patients with SARS-CoV-2 disease. On the other hand, obesity represents a state of low-grade inflammation, with various inflammatory products directly excreted by adipose tissue. In this concise report we aimed to assess common elements of obesity and SARS-CoV-2 infection. METHODS: Pubmed search on obesity and SARS-CoV-2 infection. RESULTS: We present "mechanistic" obesity-related problems that aggravate SARS-CoV-2 infection as well as tentative inflammatory/metabolic links between these diseases. CONCLUSION: Obesity and SARS-CoV-2 share common elements of the inflammatory process (and possibly also metabolic disturbances), exacerbating SARS-CoV-2 infection in the obese.
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology/etiology/metabolism[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Obesity/*complications[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/etiology/metabolism[MESH]
  • |Risk Factors[MESH]


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