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10.1016/j.cell.2020.04.007

http://scihub22266oqcxt.onion/10.1016/j.cell.2020.04.007
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32386544!8152789!32386544
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suck abstract from ncbi

pmid32386544      Cell 2020 ; 181 (4): 936-953.e20
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  • The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas #MMPMID32386544
  • Wang Q; Ding SL; Li Y; Royall J; Feng D; Lesnar P; Graddis N; Naeemi M; Facer B; Ho A; Dolbeare T; Blanchard B; Dee N; Wakeman W; Hirokawa KE; Szafer A; Sunkin SM; Oh SW; Bernard A; Phillips JW; Hawrylycz M; Koch C; Zeng H; Harris JA; Ng L
  • Cell 2020[May]; 181 (4): 936-953.e20 PMID32386544show ga
  • Recent large-scale collaborations are generating major surveys of cell types and connections in the mouse brain, collecting large amounts of data across modalities, spatial scales, and brain areas. Successful integration of these data requires a standard 3D reference atlas. Here, we present the Allen Mouse Brain Common Coordinate Framework (CCFv3) as such a resource. We constructed an average template brain at 10 mum voxel resolution by interpolating high resolution in-plane serial two-photon tomography images with 100 mum z-sampling from 1,675 young adult C57BL/6J mice. Then, using multimodal reference data, we parcellated the entire brain directly in 3D, labeling every voxel with a brain structure spanning 43 isocortical areas and their layers, 329 subcortical gray matter structures, 81 fiber tracts, and 8 ventricular structures. CCFv3 can be used to analyze, visualize, and integrate multimodal and multiscale datasets in 3D and is openly accessible (https://atlas.brain-map.org/).
  • |Animals[MESH]
  • |Atlases as Topic[MESH]
  • |Brain Mapping/methods[MESH]
  • |Brain/*anatomy & histology/*metabolism/*physiology[MESH]
  • |Image Processing, Computer-Assisted/methods[MESH]
  • |Imaging, Three-Dimensional/methods[MESH]
  • |Male[MESH]
  • |Mice[MESH]


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  • suck abstract from ncbi

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