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10.1371/journal.pntd.0008280

http://scihub22266oqcxt.onion/10.1371/journal.pntd.0008280
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32384078!7239492!32384078
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suck abstract from ncbi


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pmid32384078      PLoS+Negl+Trop+Dis 2020 ; 14 (5): e0008280
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  • Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study #MMPMID32384078
  • Huang R; Zhu L; Xue L; Liu L; Yan X; Wang J; Zhang B; Xu T; Ji F; Zhao Y; Cheng J; Wang Y; Shao H; Hong S; Cao Q; Li C; Zhao XA; Zou L; Sang D; Zhao H; Guan X; Chen X; Shan C; Xia J; Chen Y; Yan X; Wei J; Zhu C; Wu C
  • PLoS Negl Trop Dis 2020[May]; 14 (5): e0008280 PMID32384078show ga
  • Limited data are available for clinical characteristics of patients with coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe the clinical characteristics of COVID-19 and identify the risk factors for severe illness of COVID-19 in Jiangsu province, China. Clinical data of hospitalized COVID-19 patients were retrospectively collected in 8 hospitals from 8 cities of Jiangsu province, China. Clinical findings of COVID-19 patients were described and risk factors for severe illness of COVID-19 were analyzed. By Feb 10, 2020, 202 hospitalized patients with COVID-19 were enrolled. The median age of patients was 44.0 years (interquartile range, 33.0-54.0). 55 (27.2%) patients had comorbidities. At the onset of illness, the common symptoms were fever (156 [77.2%]) and cough (120 [59.4%]). 66 (32.7%) patients had lymphopenia. 193 (95.5%) patients had abnormal radiological findings. 11 (5.4%) patients were admitted to the intensive care unit and none of the patients died. 23 (11.4%) patients had severe illness. Severe illness of COVID-19 was independently associated with body mass index (BMI) >/= 28 kg/m2 (odds ratio [OR], 9.219; 95% confidence interval [CI], 2.731 to 31.126; P<0.001) and a known history of type 2 diabetes (OR, 4.326; 95% CI, 1.059 to 17.668; P = 0.041). In this case series in Jiangsu Province, COVID-19 patients had less severe symptoms and had better outcomes than the initial COVID-19 patients in Wuhan. The BMI >/= 28 kg/m2 and a known history of type 2 diabetes were independent risk factors of severe illness in patients with COVID-19.
  • |Adult[MESH]
  • |Betacoronavirus[MESH]
  • |Body Mass Index[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/diagnosis/*epidemiology/physiopathology[MESH]
  • |Cough/virology[MESH]
  • |Diabetes Mellitus, Type 2/complications[MESH]
  • |Female[MESH]
  • |Fever/virology[MESH]
  • |Hospitalization/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Lymphopenia/virology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/*epidemiology/physiopathology[MESH]
  • |Risk Factors[MESH]


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