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10.1093/cid/ciaa547 http://scihub22266oqcxt.onion/10.1093/cid/ciaa547 32382748!7239258!32382748     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Infect+Dis 2020 ; 71 (8): 2006-2013 Nephropedia Template TP {{tp|p=32382748|t=2020. Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventative and Therapeutic Strategies |pdf=|usr=}}{{32382748}} gab.com Text Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventative and Therapeutic Strategies JO: Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32382748 #FOAvip The current pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), reveals a peculiar trend of milder disease and lower case fatality in children compared with adults. Consistent epidemiologic evidence of reduced severity of infection in children across different populations and countries suggests there are underlying biological differences between children and adults that mediate differential disease pathogenesis. This presents a unique opportunity to learn about disease-modifying host factors from pediatric populations. Our review summarizes the current knowledge of pediatric clinical disease, role in transmission, risks for severe disease, protective immunity, as well as novel therapies and vaccine trials for children. We then define key hypotheses and areas for future research that can use the pediatric model of disease, transmission, and immunity to develop preventive and therapeutic strategies for people of all age groups. Twit Text FOAVip Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventative and Therapeutic Strategies ????Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32382748 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32382748 #FOAvip English Wikipedia <ref>{{Cite pmid|32382748}}</ref> Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventative and Therapeutic Strategies #MMPMID32382748 Singh T; Heston SM; Langel SN; Blasi M; Hurst JH; Fouda GG; Kelly MS; Permar SR Clin Infect Dis 2020[Nov]; 71 (8): 2006-2013 PMID32382748show ga The current pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), reveals a peculiar trend of milder disease and lower case fatality in children compared with adults. Consistent epidemiologic evidence of reduced severity of infection in children across different populations and countries suggests there are underlying biological differences between children and adults that mediate differential disease pathogenesis. This presents a unique opportunity to learn about disease-modifying host factors from pediatric populations. Our review summarizes the current knowledge of pediatric clinical disease, role in transmission, risks for severe disease, protective immunity, as well as novel therapies and vaccine trials for children. We then define key hypotheses and areas for future research that can use the pediatric model of disease, transmission, and immunity to develop preventive and therapeutic strategies for people of all age groups. |*Coronavirus Infections/drug therapy/epidemiology/immunology/transmission[MESH] |*Pandemics[MESH] |*Pneumonia, Viral/drug therapy/epidemiology/immunology/transmission[MESH] |Adolescent[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |Child[MESH] |Child, Preschool[MESH] |Comorbidity[MESH] |Humans[MESH] |Infant[MESH] |Infant, Newborn[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH]Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventativ(epmc).pdf DeepDyve Pubget Overpricing