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10.1055/s-0040-1710512

http://scihub22266oqcxt.onion/10.1055/s-0040-1710512
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32380565!7356082!32380565
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suck abstract from ncbi


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pmid32380565      Am+J+Perinatol 2020 ; 37 (8): 845-849
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  • COVID-19 in Newborns and Infants-Low Risk of Severe Disease: Silver Lining or Dark Cloud? #MMPMID32380565
  • Rawat M; Chandrasekharan P; Hicar MD; Lakshminrusimha S
  • Am J Perinatol 2020[Jun]; 37 (8): 845-849 PMID32380565show ga
  • One hundred years after the 1918 influenza pandemic, we now face another pandemic with the severe acute respiratory syndrome-novel coronavirus-2 (SARS-CoV-2). There is considerable variability in the incidence of infection and severe disease following exposure to SARS-CoV-2. Data from China and the United States suggest a low prevalence of neonates, infants, and children, with those affected not suffering from severe disease. In this article, we speculate different theories why this novel agent is sparing neonates, infants, and young children. The low severity of SARS-CoV-2 infection in this population is associated with a high incidence of asymptomatic or mildly symptomatic infection making them efficient carriers. KEY POINTS: . There is a low prevalence of novel coronavirus disease in neonates, infants, and children.. . The fetal hemoglobin may play a protective role against coronavirus in neonates.. . Immature angiotensin converting enzyme (ACE2) interferes with coronavirus entry into the cells..
  • |*Betacoronavirus/isolation & purification/physiology[MESH]
  • |*Coronavirus Infections/epidemiology/metabolism/virology[MESH]
  • |*Pandemics/statistics & numerical data[MESH]
  • |*Pneumonia, Viral/epidemiology/metabolism/virology[MESH]
  • |Age of Onset[MESH]
  • |Angiotensin-Converting Enzyme 2[MESH]
  • |Asymptomatic Diseases/epidemiology[MESH]
  • |COVID-19[MESH]
  • |Child, Preschool[MESH]
  • |Fetal Hemoglobin/*metabolism[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Peptidyl-Dipeptidase A/*metabolism[MESH]
  • |Prevalence[MESH]
  • |Protective Factors[MESH]
  • |SARS-CoV-2[MESH]


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