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10.1016/j.autrev.2020.102554 http://scihub22266oqcxt.onion/10.1016/j.autrev.2020.102554 32380316!7198427!32380316     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Autoimmun+Rev 2020 ; 19 (7): 102554 Nephropedia Template TP {{tp|p=32380316|t=2020. Convalescent plasma in Covid-19: Possible mechanisms of action |pdf=|usr=}}{{32380316}} gab.com Text Convalescent plasma in Covid-19: Possible mechanisms of action JO: Autoimmun Rev http://www.kidney.de/pget.php?&tw=1&pmid=32380316 #FOAvip Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible of the coronavirus disease 2019 (COVID-19) pandemic. Therapeutic options including antimalarials, antivirals, and vaccines are under study. Meanwhile the current pandemic has called attention over old therapeutic tools to treat infectious diseases. Convalescent plasma (CP) constitutes the first option in the current situation, since it has been successfully used in other coronaviruses outbreaks. Herein, we discuss the possible mechanisms of action of CP and their repercussion in COVID-19 pathogenesis, including direct neutralization of the virus, control of an overactive immune system (i.e., cytokine storm, Th1/Th17 ratio, complement activation) and immunomodulation of a hypercoagulable state. All these benefits of CP are expected to be better achieved if used in non-critically hospitalized patients, in the hope of reducing morbidity and mortality. Twit Text FOAVip Convalescent plasma in Covid-19: Possible mechanisms of action ????Autoimmun Rev http://www.kidney.de/pget.php?&tw=1&pmid=32380316 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32380316 #FOAvip English Wikipedia <ref>{{Cite pmid|32380316}}</ref> Convalescent plasma in Covid-19: Possible mechanisms of action #MMPMID32380316 Rojas M; Rodriguez Y; Monsalve DM; Acosta-Ampudia Y; Camacho B; Gallo JE; Rojas-Villarraga A; Ramirez-Santana C; Diaz-Coronado JC; Manrique R; Mantilla RD; Shoenfeld Y; Anaya JM Autoimmun Rev 2020[Jul]; 19 (7): 102554 PMID32380316show ga Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible of the coronavirus disease 2019 (COVID-19) pandemic. Therapeutic options including antimalarials, antivirals, and vaccines are under study. Meanwhile the current pandemic has called attention over old therapeutic tools to treat infectious diseases. Convalescent plasma (CP) constitutes the first option in the current situation, since it has been successfully used in other coronaviruses outbreaks. Herein, we discuss the possible mechanisms of action of CP and their repercussion in COVID-19 pathogenesis, including direct neutralization of the virus, control of an overactive immune system (i.e., cytokine storm, Th1/Th17 ratio, complement activation) and immunomodulation of a hypercoagulable state. All these benefits of CP are expected to be better achieved if used in non-critically hospitalized patients, in the hope of reducing morbidity and mortality. |Antibodies, Neutralizing/*therapeutic use[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |COVID-19 Serotherapy[MESH] |Clinical Trials as Topic[MESH] |Coronavirus Infections/immunology/*therapy[MESH] |Humans[MESH] |Immunization, Passive[MESH] |Lymphocytes/immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/immunology/*therapy[MESH] |Retrospective Studies[MESH]Convalescent plasma in Covid-19: Possible mechanisms of action (epmc).pdf DeepDyve Pubget Overpricing