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10.1093/infdis/jiaa252

http://scihub22266oqcxt.onion/10.1093/infdis/jiaa252
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32379887!7239156!32379887
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suck abstract from ncbi


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pmid32379887      J+Infect+Dis 2020 ; 222 (2): 198-202
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  • T-Cell Subset Counts in Peripheral Blood Can Be Used as Discriminatory Biomarkers for Diagnosis and Severity Prediction of Coronavirus Disease 2019 #MMPMID32379887
  • Jiang M; Guo Y; Luo Q; Huang Z; Zhao R; Liu S; Le A; Li J; Wan L
  • J Infect Dis 2020[Jun]; 222 (2): 198-202 PMID32379887show ga
  • This study evaluated the significance of lymphocyte subset detection in peripheral blood in the diagnosis and prognosis of coronavirus disease 2019 (COVID-19). Our results revealed that CD3+ T cells, CD4+ T cells, CD8+ T cells, and natural killer cells were significantly decreased in patients with COVID-19. These patients had a relatively slight decrease in CD4+ T cells but a severe decrease in CD8+ T cells. The significantly elevated CD4/CD8 ratio was observed in COVID-19 patients. T-cell subset counts were related to the severity and prognosis of COVID-19, suggesting that the counts of CD8+ T and CD4+ T cells can be used as diagnostic markers of COVID-19 and predictors of disease severity.
  • |*Betacoronavirus[MESH]
  • |*Clinical Laboratory Techniques[MESH]
  • |*Lymphocyte Count[MESH]
  • |*T-Lymphocyte Subsets[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Biomarkers/blood[MESH]
  • |CD4 Lymphocyte Count[MESH]
  • |CD4-CD8 Ratio[MESH]
  • |CD8-Positive T-Lymphocytes[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Coronavirus Infections/*diagnosis/*immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Killer Cells, Natural[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Patient Acuity[MESH]
  • |Pneumonia, Viral/*diagnosis/*immunology[MESH]
  • |SARS-CoV-2[MESH]
  • |Sensitivity and Specificity[MESH]


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