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10.5582/ddt.2020.01015

http://scihub22266oqcxt.onion/10.5582/ddt.2020.01015
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32378648!ä!32378648

suck abstract from ncbi


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pmid32378648      Drug+Discov+Ther 2020 ; 14 (2): 73-76
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  • Rapid review for the anti-coronavirus effect of remdesivir #MMPMID32378648
  • Li Z; Wang X; Cao D; Sun R; Li C; Li G
  • Drug Discov Ther 2020[]; 14 (2): 73-76 PMID32378648show ga
  • The outbreak of SARS-CoV-2 rapidly spread across China and worldwide. Remdesivir had been proposed as a promising option for treating coronavirus disease 2019 (COVID-19). We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. Even though remdesivir was proposed as a promising option for treating COVID-19 based on laboratory experiments and reports from compassionate use, its safety and effect in humans requires high-quality evidence from well-designed and adequately-powered clinical trials for further clarification.
  • |Adenosine Monophosphate/*analogs & derivatives/therapeutic use[MESH]
  • |Alanine/*analogs & derivatives/therapeutic use[MESH]
  • |Animals[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Betacoronavirus/drug effects[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Drug Evaluation, Preclinical[MESH]
  • |Humans[MESH]
  • |Middle East Respiratory Syndrome Coronavirus/drug effects[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]
  • |SARS-CoV-2[MESH]


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