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Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Drug+Discov+Ther 2020 ; 14 (2): 100-102 Nephropedia Template TP
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Treat 2019 novel coronavirus (COVID-19) with IL-6 inhibitor: Are we already that far? #MMPMID32378647
Zhang Y; Zhong Y; Pan L; Dong J
Drug Discov Ther 2020[]; 14 (2): 100-102 PMID32378647show ga
The world is in the midst of the coronavirus disease 2019 (COVID-19) pandemic. Interleukin 6 (IL-6) inhibitor (tocilizumab) had been suggested for the treatment of acute respiratory distress syndrome (ARDS) patients based on the concept of "cytokine storm" in COVID-19. However, we still lack reliable studies to verify "cytokine storm" in COVID-19 pneumonia. Furthermore, IL-6 inhibitor has potential hazards of inducing infectious diseases. The efficacy of IL-6 monoclonal antibody-directed therapy remains to be fully evaluated.