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10.5582/ddt.2020.03006

http://scihub22266oqcxt.onion/10.5582/ddt.2020.03006
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32378647!ä!32378647

suck abstract from ncbi


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pmid32378647      Drug+Discov+Ther 2020 ; 14 (2): 100-102
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  • Treat 2019 novel coronavirus (COVID-19) with IL-6 inhibitor: Are we already that far? #MMPMID32378647
  • Zhang Y; Zhong Y; Pan L; Dong J
  • Drug Discov Ther 2020[]; 14 (2): 100-102 PMID32378647show ga
  • The world is in the midst of the coronavirus disease 2019 (COVID-19) pandemic. Interleukin 6 (IL-6) inhibitor (tocilizumab) had been suggested for the treatment of acute respiratory distress syndrome (ARDS) patients based on the concept of "cytokine storm" in COVID-19. However, we still lack reliable studies to verify "cytokine storm" in COVID-19 pneumonia. Furthermore, IL-6 inhibitor has potential hazards of inducing infectious diseases. The efficacy of IL-6 monoclonal antibody-directed therapy remains to be fully evaluated.
  • |Antibodies, Monoclonal, Humanized/*therapeutic use[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Cytokines/adverse effects[MESH]
  • |Humans[MESH]
  • |Interleukin-6[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]
  • |Receptors, Interleukin-6/*antagonists & inhibitors[MESH]


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