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10.1186/s12987-020-00196-2 http://scihub22266oqcxt.onion/10.1186/s12987-020-00196-2 32375819!7201396!32375819     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Fluids+Barriers+CNS 2020 ; 17 (1): 35 Nephropedia Template TP {{tp|p=32375819|t=2020. Choroid plexus and the blood-cerebrospinal fluid barrier in disease |pdf=|usr=}}{{32375819}} gab.com Text Choroid plexus and the blood-cerebrospinal fluid barrier in disease JO: Fluids Barriers CNS http://www.kidney.de/pget.php?&tw=1&pmid=32375819 #FOAvip The choroid plexus (CP) forming the blood-cerebrospinal fluid (B-CSF) barrier is among the least studied structures of the central nervous system (CNS) despite its clinical importance. The CP is an epithelio-endothelial convolute comprising a highly vascularized stroma with fenestrated capillaries and a continuous lining of epithelial cells joined by apical tight junctions (TJs) that are crucial in forming the B-CSF barrier. Integrity of the CP is critical for maintaining brain homeostasis and B-CSF barrier permeability. Recent experimental and clinical research has uncovered the significance of the CP in the pathophysiology of various diseases affecting the CNS. The CP is involved in penetration of various pathogens into the CNS, as well as the development of neurodegenerative (e.g., Alzheimer s disease) and autoimmune diseases (e.g., multiple sclerosis). Moreover, the CP was shown to be important for restoring brain homeostasis following stroke and trauma. In addition, new diagnostic methods and treatment of CP papilloma and carcinoma have recently been developed. This review describes and summarizes the current state of knowledge with regard to the roles of the CP and B-CSF barrier in the pathophysiology of various types of CNS diseases and sets up the foundation for further avenues of research. Twit Text FOAVip Choroid plexus and the blood-cerebrospinal fluid barrier in disease ????Fluids Barriers CNS http://www.kidney.de/pget.php?&tw=1&pmid=32375819 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32375819 #FOAvip English Wikipedia <ref>{{Cite pmid|32375819}}</ref> Choroid plexus and the blood-cerebrospinal fluid barrier in disease #MMPMID32375819 Solar P; Zamani A; Kubickova L; Dubovy P; Joukal M Fluids Barriers CNS 2020[May]; 17 (1): 35 PMID32375819show ga The choroid plexus (CP) forming the blood-cerebrospinal fluid (B-CSF) barrier is among the least studied structures of the central nervous system (CNS) despite its clinical importance. The CP is an epithelio-endothelial convolute comprising a highly vascularized stroma with fenestrated capillaries and a continuous lining of epithelial cells joined by apical tight junctions (TJs) that are crucial in forming the B-CSF barrier. Integrity of the CP is critical for maintaining brain homeostasis and B-CSF barrier permeability. Recent experimental and clinical research has uncovered the significance of the CP in the pathophysiology of various diseases affecting the CNS. The CP is involved in penetration of various pathogens into the CNS, as well as the development of neurodegenerative (e.g., Alzheimer s disease) and autoimmune diseases (e.g., multiple sclerosis). Moreover, the CP was shown to be important for restoring brain homeostasis following stroke and trauma. In addition, new diagnostic methods and treatment of CP papilloma and carcinoma have recently been developed. This review describes and summarizes the current state of knowledge with regard to the roles of the CP and B-CSF barrier in the pathophysiology of various types of CNS diseases and sets up the foundation for further avenues of research. |*Central Nervous System Diseases/immunology/metabolism/physiopathology[MESH] |Animals[MESH] |Cerebrospinal Fluid/*metabolism[MESH] |Choroid Plexus/*anatomy & histology/*physiology[MESH] |Homeostasis/*physiology[MESH]Choroid plexus and the blood-cerebrospinal fluid barrier in disease (epmc).pdf DeepDyve Pubget Overpricing