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10.3390/biomedicines8050109 http://scihub22266oqcxt.onion/10.3390/biomedicines8050109 32375268!7277397!32375268     free     free     free       Biomedicines 2020 ; 8 (5): ä Nephropedia Template TP {{tp|p=32375268|t=2020. Coronavirus Pandemic-Therapy and Vaccines |pdf=|usr=}}{{32375268}} gab.com Text Coronavirus Pandemic-Therapy and Vaccines JO: Biomedicines http://www.kidney.de/pget.php?&tw=1&pmid=32375268 #FOAvip The current coronavirus COVID-19 pandemic, which originated in Wuhan, China, has raised significant social, psychological and economic concerns in addition to direct medical issues. The rapid spread of severe acute respiratory syndrome-coronavirus (SARS-CoV)-2 to almost every country on the globe and the failure to contain the infections have contributed to fear and panic worldwide. The lack of available and efficient antiviral drugs or vaccines has further worsened the situation. For these reasons, it cannot be overstated that an accelerated effort for the development of novel drugs and vaccines is needed. In this context, novel approaches in both gene therapy and vaccine development are essential. Previous experience from SARS- and MERS-coronavirus vaccine and drug development projects have targeted glycoprotein epitopes, monoclonal antibodies, angiotensin receptor blockers and gene silencing technologies, which may be useful for COVID-19 too. Moreover, existing antivirals used for other types of viral infections have been considered as urgent action is necessary. This review aims at providing a background of coronavirus genetics and biology, examples of therapeutic and vaccine strategies taken and potential innovative novel approaches in progress. Twit Text FOAVip Coronavirus Pandemic-Therapy and Vaccines ????Biomedicines http://www.kidney.de/pget.php?&tw=1&pmid=32375268 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32375268 #FOAvip English Wikipedia <ref>{{Cite pmid|32375268}}</ref> Coronavirus Pandemic-Therapy and Vaccines #MMPMID32375268 Lundstrom K Biomedicines 2020[May]; 8 (5): ä PMID32375268show ga The current coronavirus COVID-19 pandemic, which originated in Wuhan, China, has raised significant social, psychological and economic concerns in addition to direct medical issues. The rapid spread of severe acute respiratory syndrome-coronavirus (SARS-CoV)-2 to almost every country on the globe and the failure to contain the infections have contributed to fear and panic worldwide. The lack of available and efficient antiviral drugs or vaccines has further worsened the situation. For these reasons, it cannot be overstated that an accelerated effort for the development of novel drugs and vaccines is needed. In this context, novel approaches in both gene therapy and vaccine development are essential. Previous experience from SARS- and MERS-coronavirus vaccine and drug development projects have targeted glycoprotein epitopes, monoclonal antibodies, angiotensin receptor blockers and gene silencing technologies, which may be useful for COVID-19 too. Moreover, existing antivirals used for other types of viral infections have been considered as urgent action is necessary. This review aims at providing a background of coronavirus genetics and biology, examples of therapeutic and vaccine strategies taken and potential innovative novel approaches in progress. äCoronavirus Pandemic-Therapy and Vaccines (epmc).pdf DeepDyve Pubget Overpricing