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10.1016/j.trim.2020.101304

http://scihub22266oqcxt.onion/10.1016/j.trim.2020.101304
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32371150!7194049!32371150
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suck abstract from ncbi


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pmid32371150      Transpl+Immunol 2020 ; 61 (ä): 101304
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  • Immediate impact of COVID-19 on transplant activity in the Netherlands #MMPMID32371150
  • de Vries APJ; Alwayn IPJ; Hoek RAS; van den Berg AP; Ultee FCW; Vogelaar SM; Haase-Kromwijk BJJM; Heemskerk MBA; Hemke AC; Nijboer WN; Schaefer BS; Kuiper MA; de Jonge J; van der Kaaij NP; Reinders MEJ
  • Transpl Immunol 2020[Aug]; 61 (ä): 101304 PMID32371150show ga
  • The rapid emergence of the COVID-19 pandemic is unprecedented and poses an unparalleled obstacle in the sixty-five year history of organ transplantation. Worldwide, the delivery of transplant care is severely challenged by matters concerning - but not limited to - organ procurement, risk of SARS-CoV-2 transmission, screening strategies of donors and recipients, decisions to postpone or proceed with transplantation, the attributable risk of immunosuppression for COVID-19 and entrenched health care resources and capacity. The transplant community is faced with choosing a lesser of two evils: initiating immunosuppression and potentially accepting detrimental outcome when transplant recipients develop COVID-19 versus postponing transplantation and accepting associated waitlist mortality. Notably, prioritization of health care services for COVID-19 care raises concerns about allocation of resources to deliver care for transplant patients who might otherwise have excellent 1-year and 10-year survival rates. Children and young adults with end-stage organ disease in particular seem more disadvantaged by withholding transplantation because of capacity issues than from medical consequences of SARS-CoV-2. This report details the nationwide response of the Dutch transplant community to these issues and the immediate consequences for transplant activity. Worrisome, there was a significant decrease in organ donation numbers affecting all organ transplant services. In addition, there was a detrimental effect on transplantation numbers in children with end-organ failure. Ongoing efforts focus on mitigation of not only primary but also secondary harm of the pandemic and to find right definitions and momentum to restore the transplant programs.
  • |Adolescent[MESH]
  • |Betacoronavirus/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Coronavirus Infections/*epidemiology/*transmission[MESH]
  • |Humans[MESH]
  • |Netherlands[MESH]
  • |Organ Transplantation/*statistics & numerical data[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/*transmission[MESH]
  • |SARS-CoV-2[MESH]
  • |Tissue and Organ Procurement[MESH]


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