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10.1016/j.cmet.2020.04.021 http://scihub22266oqcxt.onion/10.1016/j.cmet.2020.04.021 32369736!7252168!32369736     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32369736&cmd=llinks): Failed to open stream: HTTP request failed! 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Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes |pdf=|usr=}}{{32369736}} gab.com Text Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes JO: Cell Metab http://www.kidney.de/pget.php?&tw=1&pmid=32369736 #FOAvip Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D. Twit Text FOAVip Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes ????Cell Metab http://www.kidney.de/pget.php?&tw=1&pmid=32369736 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32369736 #FOAvip English Wikipedia <ref>{{Cite pmid|32369736}}</ref> Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes #MMPMID32369736 Zhu L; She ZG; Cheng X; Qin JJ; Zhang XJ; Cai J; Lei F; Wang H; Xie J; Wang W; Li H; Zhang P; Song X; Chen X; Xiang M; Zhang C; Bai L; Xiang D; Chen MM; Liu Y; Yan Y; Liu M; Mao W; Zou J; Liu L; Chen G; Luo P; Xiao B; Zhang C; Zhang Z; Lu Z; Wang J; Lu H; Xia X; Wang D; Liao X; Peng G; Ye P; Yang J; Yuan Y; Huang X; Guo J; Zhang BH; Li H Cell Metab 2020[Jun]; 31 (6): 1068-1077.e3 PMID32369736show ga Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio [HR], 1.49) and multiple organ injury than the non-diabetic individuals. Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D. |Aged[MESH] |Betacoronavirus/pathogenicity[MESH] |Blood Glucose/*analysis[MESH] |COVID-19[MESH] |Coronavirus Infections/complications/*mortality/pathology[MESH] |Diabetes Mellitus, Type 2/*blood/complications[MESH] |Disease Susceptibility/pathology[MESH] |Female[MESH] |Glycemic Index/*physiology[MESH] |Hospitalization/statistics & numerical data[MESH] |Humans[MESH] |Hyperglycemia/*blood/complications[MESH] |Hypoglycemic Agents/therapeutic use[MESH] |Longitudinal Studies[MESH] |Male[MESH] |Middle Aged[MESH] |Multiple Organ Failure/complications/mortality[MESH] |Pandemics[MESH] |Pneumonia, Viral/complications/*mortality/pathology[MESH] |Retrospective Studies[MESH]Association of Blood Glucose Control and Outcomes in Patients with COV(epmc).pdf DeepDyve Pubget Overpricing