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10.1038/s41467-020-16256-y

http://scihub22266oqcxt.onion/10.1038/s41467-020-16256-y

32366817!7198537!32366817
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      Nat+Commun 2020 ; 11 (1): 2251
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A human monoclonal antibody blocking SARS-CoV-2 infection JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=32366817 #FOAvip The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.
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A human monoclonal antibody blocking SARS-CoV-2 infection ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=32366817 #FOAvip
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<ref>{{Cite pmid|32366817}}</ref>

A human monoclonal antibody blocking SARS-CoV-2 infection #MMPMID32366817
Wang C; Li W; Drabek D; Okba NMA; van Haperen R; Osterhaus ADME; van Kuppeveld FJM; Haagmans BL; Grosveld F; Bosch BJ
Nat Commun 2020[May]; 11 (1): 2251 PMID32366817show ga
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.
|Angiotensin-Converting Enzyme 2[MESH]
|Animals[MESH]
|Antibodies, Monoclonal/*immunology/pharmacology[MESH]
|Antibodies, Neutralizing/*immunology/pharmacology[MESH]
|Antibodies, Viral/*immunology/pharmacology[MESH]
|Antibody Affinity/immunology[MESH]
|Betacoronavirus/chemistry/drug effects/*immunology[MESH]
|COVID-19[MESH]
|Chlorocebus aethiops[MESH]
|Conserved Sequence[MESH]
|Coronavirus Infections/drug therapy/*immunology/*prevention & control/virology[MESH]
|Cross Reactions/immunology[MESH]
|Epitopes, B-Lymphocyte/chemistry/immunology[MESH]
|Humans[MESH]
|In Vitro Techniques[MESH]
|Inhibitory Concentration 50[MESH]
|Models, Molecular[MESH]
|Pandemics/*prevention & control[MESH]
|Peptidyl-Dipeptidase A/chemistry/metabolism[MESH]
|Pneumonia, Viral/drug therapy/*immunology/*prevention & control/virology[MESH]
|Protein Binding/drug effects[MESH]
|Protein Domains/immunology[MESH]
|Receptors, Virus/chemistry/metabolism[MESH]
|SARS-CoV-2[MESH]
|Severe acute respiratory syndrome-related coronavirus/chemistry/drug effects/immunology[MESH]
|Spike Glycoprotein, Coronavirus/chemistry/immunology[MESH]A human monoclonal antibody blocking SARS-CoV-2 infection (epmc).pdf

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