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10.1093/cid/ciaa524

http://scihub22266oqcxt.onion/10.1093/cid/ciaa524
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32361747!7197597!32361747
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suck abstract from ncbi


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pmid32361747      Clin+Infect+Dis 2020 ; 71 (10): 2736-2743
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  • Coronavirus Disease 2019, Superinfections, and Antimicrobial Development: What Can We Expect? #MMPMID32361747
  • Clancy CJ; Nguyen MH
  • Clin Infect Dis 2020[Dec]; 71 (10): 2736-2743 PMID32361747show ga
  • Coronavirus disease 2019 (COVID-19) arose at a time of great concern about antimicrobial resistance (AMR). No studies have specifically assessed COVID-19-associated superinfections or AMR. Based on limited data from case series, it is reasonable to anticipate that an appreciable minority of patients with severe COVID-19 will develop superinfections, most commonly pneumonia due to nosocomial bacteria and Aspergillus. Microbiology and AMR patterns are likely to reflect institutional ecology. Broad-spectrum antimicrobial use is likely to be widespread among hospitalized patients, both as directed and empiric therapy. Stewardship will have a crucial role in limiting unnecessary antimicrobial use and AMR. Congressional COVID-19 relief bills are considering antimicrobial reimbursement reforms and antimicrobial subscription models, but it is unclear if these will be included in final legislation. Prospective studies on COVID-19 superinfections are needed, data from which can inform rational antimicrobial treatment and stewardship strategies, and models for market reform and sustainable drug development.
  • |*Anti-Infective Agents/therapeutic use[MESH]
  • |*COVID-19[MESH]
  • |*Superinfection/drug therapy[MESH]
  • |Anti-Bacterial Agents/therapeutic use[MESH]
  • |Humans[MESH]
  • |Prospective Studies[MESH]


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