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10.1016/j.bbadis.2020.165823

http://scihub22266oqcxt.onion/10.1016/j.bbadis.2020.165823
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suck abstract from ncbi


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pmid32360589      Biochim+Biophys+Acta+Mol+Basis+Dis 2020 ; 1866 (10): 165823
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  • Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs #MMPMID32360589
  • Scheffer DDL; Latini A
  • Biochim Biophys Acta Mol Basis Dis 2020[Oct]; 1866 (10): 165823 PMID32360589show ga
  • A wide array of molecular pathways has been investigated during the past decade in order to understand the mechanisms by which the practice of physical exercise promotes neuroprotection and reduces the risk of developing communicable and non-communicable chronic diseases. While a single session of physical exercise may represent a challenge for cell homeostasis, repeated physical exercise sessions will improve immunosurveillance and immunocompetence. Additionally, immune cells from the central nervous system will acquire an anti-inflammatory phenotype, protecting central functions from age-induced cognitive decline. This review highlights the exercise-induced anti-inflammatory effect on the prevention or treatment of common chronic clinical and experimental settings. It also suggests the use of pterins in biological fluids as sensitive biomarkers to follow the anti-inflammatory effect of physical exercise.
  • |Animals[MESH]
  • |Anti-Inflammatory Agents/*pharmacology[MESH]
  • |Biomarkers[MESH]
  • |Blood-Brain Barrier/immunology[MESH]
  • |Chronic Disease[MESH]
  • |Communicable Diseases/immunology[MESH]
  • |Cytokines[MESH]
  • |Databases, Factual[MESH]
  • |Exercise/*physiology[MESH]
  • |Humans[MESH]
  • |Immune System/*drug effects/*immunology[MESH]
  • |Immunity, Innate/immunology[MESH]
  • |Inflammation/immunology[MESH]
  • |Neopterin/pharmacology[MESH]


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