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10.1016/j.phrs.2020.104849 http://scihub22266oqcxt.onion/10.1016/j.phrs.2020.104849 32360482!7189871!32360482     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmacol+Res 2020 ; 157 (ä): 104849 Nephropedia Template TP {{tp|p=32360482|t=2020. NSAIDs in patients with viral infections, including Covid-19: Victims or perpetrators?|pdf=|usr=}}{{32360482}} gab.com Text NSAIDs in patients with viral infections, including Covid-19: Victims or perpetrators JO: Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=32360482 #FOAvip Taking anti-inflammatory drugs, including non-steroidal (NSAIDs), during Covid-19 infection, how much is risky? The French Minister of Health, who has raised an alarm on a possible risk deriving from the use of ibuprofen for the control of fever and other symptoms during the disease, opened the debate a few days ago. In this paper we examine available evidence from preclinical and clinical studies that had analysed the role of COX in the inflammatory process and the effects of NSAIDs in patients with infections. Most of the published studies that suggested not protective effects of NSAIDs were mainly performed in vitro or on animals. Therefore, their meaning in humans is to be considered with great caution. Based also on data suggesting protective effects of NSAIDs, we concluded that currently there is no evidence suggesting a correlation between NSAIDs and a worsening of infections. Further studies will be certainly needed to better define the role of NSAIDs and particularly COX2 inhibitors in patients with infections. In the meantime, we must wait for results of the revision started by the PRAC on May 2019 on the association ibuprofen/ketoprofen?????? and worsening of infections. Since nowadays no scientific evidence establishes a correlation between NSAIDS and worsening of COVID-19, patients should be advice against any NSAIDs self-medication when COVID-19 like symptoms are present. Twit Text FOAVip NSAIDs in patients with viral infections, including Covid-19: Victims or perpetrators ????Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=32360482 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32360482 #FOAvip English Wikipedia <ref>{{Cite pmid|32360482}}</ref> NSAIDs in patients with viral infections, including Covid-19: Victims or perpetrators? #MMPMID32360482 Capuano A; Scavone C; Racagni G; Scaglione F Pharmacol Res 2020[Jul]; 157 (ä): 104849 PMID32360482show ga Taking anti-inflammatory drugs, including non-steroidal (NSAIDs), during Covid-19 infection, how much is risky? The French Minister of Health, who has raised an alarm on a possible risk deriving from the use of ibuprofen for the control of fever and other symptoms during the disease, opened the debate a few days ago. In this paper we examine available evidence from preclinical and clinical studies that had analysed the role of COX in the inflammatory process and the effects of NSAIDs in patients with infections. Most of the published studies that suggested not protective effects of NSAIDs were mainly performed in vitro or on animals. Therefore, their meaning in humans is to be considered with great caution. Based also on data suggesting protective effects of NSAIDs, we concluded that currently there is no evidence suggesting a correlation between NSAIDs and a worsening of infections. Further studies will be certainly needed to better define the role of NSAIDs and particularly COX2 inhibitors in patients with infections. In the meantime, we must wait for results of the revision started by the PRAC on May 2019 on the association ibuprofen/ketoprofen?????? and worsening of infections. Since nowadays no scientific evidence establishes a correlation between NSAIDS and worsening of COVID-19, patients should be advice against any NSAIDs self-medication when COVID-19 like symptoms are present. |Animals[MESH] |Anti-Inflammatory Agents, Non-Steroidal/*adverse effects/therapeutic use[MESH] |Anti-Inflammatory Agents/*adverse effects/therapeutic use[MESH] |Betacoronavirus/drug effects[MESH] |COVID-19[MESH] |Coronavirus Infections/*drug therapy[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH] |SARS-CoV-2[MESH]NSAIDs in patients with viral infections, including Covid-19: Victims (epmc).pdf DeepDyve Pubget Overpricing