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10.1016/j.jmii.2020.04.013

http://scihub22266oqcxt.onion/10.1016/j.jmii.2020.04.013
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32359943!7185000!32359943
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suck abstract from ncbi


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pmid32359943      J+Microbiol+Immunol+Infect 2021 ; 54 (1): 54-60
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  • A cluster of health care workers with COVID-19 pneumonia caused by SARS-CoV-2 #MMPMID32359943
  • Wei XS; Wang XR; Zhang JC; Yang WB; Ma WL; Yang BH; Jiang NC; Gao ZC; Shi HZ; Zhou Q
  • J Microbiol Immunol Infect 2021[Feb]; 54 (1): 54-60 PMID32359943show ga
  • BACKGROUND: The current outbreak of coronavirus disease 2019 (COVID-19) caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, Hubei, China, spreads across national and international borders. METHODS: We prospectively collected medical records of 14 health care workers (HCWs) who were infected with SARS-CoV-2, in neurosurgery department of Wuhan Union Hospital, China. RESULTS: Among the 14 HCWs, 12 were conformed cases, the other 2 were suspected cases. Most of them were either exposed to the two index patients or infected coworkers, without knowing they were COVID-19 patients. There were 4 male and 10 female infected HCWs in this cohort, whose mean age was 36 years (SD, 6 years). The main symptoms included myalgia or fatigue (100%), fever (86%) and dry cough (71%). On admission, 79% of infected HCWs showed leucopenia and 43% lymphopenia. Reduced complement C3 could be seen in 57% of the infected HCWs and IL-6 was significantly elevated in 86% of them. The proportion of lymphocytes subsets, concentrations of immunoglobulins, complement C4, IL-2, IL-4, IL-10, TNF-alpha and IFN-gamma were within normal range in these 14 infected HCWs. The most frequent findings on pulmonary computed tomographic images were bilateral multifocal ground-glass opacifications (86%). CONCLUSIONS: Human-to-human transmission of COVID-19 pneumonia has occurred among HCWs, and most of these infected HCWs with confirmed COVID-19 are mild cases. Our data suggest that in the epidemic area of COVID-19, stringent and urgent surveillance and infection-control measures should be implemented to protect doctors and nurses from COVID-19 infection.
  • |*Disease Hotspot[MESH]
  • |*Health Personnel[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/diagnosis/*epidemiology/therapy[MESH]
  • |Cross Infection/diagnosis/*epidemiology/therapy[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infection Control[MESH]
  • |Infectious Disease Transmission, Patient-to-Professional[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neurosurgery[MESH]
  • |Occupational Diseases/diagnosis/*epidemiology/therapy[MESH]
  • |Prospective Studies[MESH]
  • |Surgery Department, Hospital[MESH]


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