COVID-19: a case for inhibiting IL-17? #MMPMID32358580
Pacha O; Sallman MA; Evans SE
Nat Rev Immunol 2020[Jun]; 20 (6): 345-346 PMID32358580show ga
IL-17 and IL-17 receptor inhibitors boast an impressive safety history and are widely available. Here, we argue that targeting IL-17 is immunologically plausible as a strategy to prevent acute respiratory distress syndrome (ARDS) in coronavirus disease 2019 (COVID-19) and discuss why we think that a clinical trial of a drug in this class could be a logical addition to the effort to find effective therapies.