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10.3390/v12050487 http://scihub22266oqcxt.onion/10.3390/v12050487 32357558!7291293!32357558     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2020 ; 12 (5): ä Nephropedia Template TP {{tp|p=32357558|t=2020. Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections |pdf=|usr=}}{{32357558}} gab.com Text Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32357558 #FOAvip Virus infection has drawn extensive attention since it causes serious or even deadly diseases, consequently inducing a series of social and public health problems. Caveolin-1 is the most important structural protein of caveolae, a membrane invagination widely known for its role in endocytosis and subsequent cytoplasmic transportation. Caveolae/caveolin-1 is tightly associated with a wide range of biological processes, including cholesterol homeostasis, cell mechano-sensing, tumorigenesis, and signal transduction. Intriguingly, the versatile roles of caveolae/caveolin-1 in virus infections have increasingly been appreciated. Over the past few decades, more and more viruses have been identified to invade host cells via caveolae-mediated endocytosis, although other known pathways have been explored. The subsequent post-entry events, including trafficking, replication, assembly, and egress of a large number of viruses, are caveolae/caveolin-1-dependent. Deprivation of caveolae/caveolin-1 by drug application or gene editing leads to abnormalities in viral uptake, viral protein expression, or virion release, whereas the underlying mechanisms remain elusive and must be explored holistically to provide potential novel antiviral targets and strategies. This review recapitulates our current knowledge on how caveolae/caveolin-1 functions in every step of the viral infection cycle and various relevant signaling pathways, hoping to provide a new perspective for future viral cell biology research. Twit Text FOAVip Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32357558 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32357558 #FOAvip English Wikipedia <ref>{{Cite pmid|32357558}}</ref> Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections #MMPMID32357558 Xing Y; Wen Z; Gao W; Lin Z; Zhong J; Jiu Y Viruses 2020[Apr]; 12 (5): ä PMID32357558show ga Virus infection has drawn extensive attention since it causes serious or even deadly diseases, consequently inducing a series of social and public health problems. Caveolin-1 is the most important structural protein of caveolae, a membrane invagination widely known for its role in endocytosis and subsequent cytoplasmic transportation. Caveolae/caveolin-1 is tightly associated with a wide range of biological processes, including cholesterol homeostasis, cell mechano-sensing, tumorigenesis, and signal transduction. Intriguingly, the versatile roles of caveolae/caveolin-1 in virus infections have increasingly been appreciated. Over the past few decades, more and more viruses have been identified to invade host cells via caveolae-mediated endocytosis, although other known pathways have been explored. The subsequent post-entry events, including trafficking, replication, assembly, and egress of a large number of viruses, are caveolae/caveolin-1-dependent. Deprivation of caveolae/caveolin-1 by drug application or gene editing leads to abnormalities in viral uptake, viral protein expression, or virion release, whereas the underlying mechanisms remain elusive and must be explored holistically to provide potential novel antiviral targets and strategies. This review recapitulates our current knowledge on how caveolae/caveolin-1 functions in every step of the viral infection cycle and various relevant signaling pathways, hoping to provide a new perspective for future viral cell biology research. |*Virus Physiological Phenomena[MESH] |Animals[MESH] |Caveolae/metabolism/*virology[MESH] |Caveolin 1/genetics/*metabolism[MESH] |Endocytosis[MESH] |Humans[MESH] |Virus Diseases/genetics/*metabolism/physiopathology/virology[MESH]Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infec(epmc).pdf DeepDyve Pubget Overpricing