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10.1002/cpt.1879

http://scihub22266oqcxt.onion/10.1002/cpt.1879
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32356569!7267567!32356569
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suck abstract from ncbi


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pmid32356569      Clin+Pharmacol+Ther 2020 ; 108 (4): 699-702
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  • Challenges in Drug Development Posed by the COVID-19 Pandemic: An Opportunity for Clinical Pharmacology #MMPMID32356569
  • Venkatakrishnan K; Yalkinoglu O; Dong JQ; Benincosa LJ
  • Clin Pharmacol Ther 2020[Oct]; 108 (4): 699-702 PMID32356569show ga
  • The unprecedented challenges posed by the coronavirus disease 2019 (COVID-19) pandemic highlight the urgency for applying clinical pharmacology and model-informed drug development in (i) dosage optimization for COVID-19 therapies, (ii) approaching therapeutic dilemmas in clinical trial settings, and (iii) maximizing value of information from impacted non-COVID-19 trials. More than ever, we have a responsibility for adaptive evidence synthesis with a Totality of Evidence mindset in this race against time across biomedical research, clinical practice, drug development, and regulation.
  • |*Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Clinical Trials as Topic/*methods/standards[MESH]
  • |Coronavirus Infections/*drug therapy/epidemiology[MESH]
  • |Drug Development/*methods/standards[MESH]
  • |Humans[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pharmacology, Clinical/*methods/standards[MESH]
  • |Pneumonia, Viral/*drug therapy/epidemiology[MESH]


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