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10.1097/RTI.0000000000000530

http://scihub22266oqcxt.onion/10.1097/RTI.0000000000000530
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32349055!7253049!32349055
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suck abstract from ncbi


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pmid32349055      J+Thorac+Imaging 2020 ; 35 (6): 344-345
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  • Is COVID Evolution Due to Occurrence of Pulmonary Vascular Thrombosis? #MMPMID32349055
  • Saba L; Sverzellati N
  • J Thorac Imaging 2020[Nov]; 35 (6): 344-345 PMID32349055show ga
  • In this hypothesis paper, we suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce intravascular pulmonary thrombosis, which may result in the rapid worsening of clinical conditions and, eventually, exitus. Previously published papers have demonstrated that increased levels of D-dimer at hospital admission correlate with a more severe disease (0.5 mg/L) or occurrence of death (1 mg/L). The potential prothrombotic action of the SARS-CoV-2 is supported by the topographical involvement of the lung regions with a predilection for the lower lobe with peripheral involvement. If this hypothesis is demonstrated, this could suggest the benefit of using antithrombotic/coagulation regimens for SARS-CoV-2 and, at the same time, the urgency to identify drugs that could alter the inflammatory storm, thus protecting the vessel wall.
  • |COVID-19/blood/*complications/*physiopathology[MESH]
  • |Fibrin Fibrinogen Degradation Products/metabolism[MESH]
  • |Humans[MESH]
  • |Lung Diseases/blood/etiology/physiopathology[MESH]
  • |Lung/physiopathology[MESH]
  • |SARS-CoV-2[MESH]


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