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32348052!ä!32348052

suck abstract from ncbi


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pmid32348052      Rev+Med+Suisse 2020 ; 16 (N degrees 691-2): 852-854
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  • Traitements aggravant une infection par le COVID-19 : vraiment ? #MMPMID32348052
  • Rothuizen LE; Livio F; Buclin T
  • Rev Med Suisse 2020[Apr]; 16 (N degrees 691-2): 852-854 PMID32348052show ga
  • The safety of NSAIDs, corticosteroids and renin-angiotensin inhibitors in COVID-19 is challenged. NSAIDs may interfere with the defense process against viral infection and are best avoided. Systemic corticosteroids have not shown benefit in viral infection, including other coronavirus; thus they should be avoided, unless prescribed for another indication. The benefit-risk ratio is however clearly in favor of continuing inhaled corticosteroids in patients with asthma or COPD. ACE inhibitors and sartans upregulate the expression of angiotensin-converting enzyme 2 (ACE2), the pulmonary receptor for SARS-CoV-2. Any possible clinical impact of these treatments on COVID-19 infection remains to be clarified; in the meantime, they should be continued.
  • |*Adrenal Cortex Hormones/administration & dosage/adverse effects[MESH]
  • |*Betacoronavirus[MESH]
  • |*Coronavirus Infections/complications/epidemiology[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/complications/epidemiology[MESH]
  • |Angiotensin-Converting Enzyme Inhibitors/*administration & dosage[MESH]
  • |Anti-Inflammatory Agents, Non-Steroidal/administration & dosage/adverse effects[MESH]
  • |COVID-19[MESH]
  • |Humans[MESH]


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