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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Euro+Surveill 2020 ; 25 (16): ä Nephropedia Template TP
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Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 #MMPMID32347200
Tostmann A; Bradley J; Bousema T; Yiek WK; Holwerda M; Bleeker-Rovers C; Ten Oever J; Meijer C; Rahamat-Langendoen J; Hopman J; van der Geest-Blankert N; Wertheim H
Euro Surveill 2020[Apr]; 25 (16): ä PMID32347200show ga
Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.