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10.1038/s41577-020-0323-4

http://scihub22266oqcxt.onion/10.1038/s41577-020-0323-4
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32346094!7187801!32346094
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suck abstract from ncbi


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pmid32346094      Nat+Rev+Immunol 2020 ; 20 (6): 347-348
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  • COVID-19 vaccine design: the Janus face of immune enhancement #MMPMID32346094
  • Hotez PJ; Corry DB; Bottazzi ME
  • Nat Rev Immunol 2020[Jun]; 20 (6): 347-348 PMID32346094show ga
  • Previous work on severe acute respiratory syndrome coronavirus (SARS-CoV) vaccines identified cellular immunopathology and antibody-dependent enhancement as potential safety issues. We discuss the implications of these findings for COVID-19 vaccine development and our approach to optimizing for safety and efficacy.
  • |*Drug Design[MESH]
  • |*Viral Vaccines/immunology[MESH]
  • |Animals[MESH]
  • |Antibodies, Viral/immunology[MESH]
  • |Betacoronavirus/immunology[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Coronavirus Infections/diagnosis/*immunology/prevention & control[MESH]
  • |Humans[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Pneumonia, Viral/*immunology/prevention & control[MESH]


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