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10.1136/bmjdrc-2020-001343 http://scihub22266oqcxt.onion/10.1136/bmjdrc-2020-001343 32345579!7222577!32345579     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMJ+Open+Diabetes+Res+Care 2020 ; 8 (1): ä Nephropedia Template TP {{tp|p=32345579|t=2020. Clinical characteristics and outcomes of patients with severe covid-19 with diabetes |pdf=|usr=}}{{32345579}} gab.com Text Clinical characteristics and outcomes of patients with severe covid-19 with diabetes JO: BMJ Open Diabetes Res Care http://www.kidney.de/pget.php?&tw=1&pmid=32345579 #FOAvip OBJECTIVE: This study explores the clinical characteristics of patients with diabetes with severe covid-19, and the association of diabetes with survival duration in patients with severe covid-19. RESEARCH DESIGN AND METHODS: In this single-center, retrospective, observational study, the clinical and laboratory characteristics of 193 patients with severe covid-19 were collected. 48 patients with severe covid-19 had diabetes, and 145 patients (ie, the controls) did not have diabetes. A severe case was defined as including at least one of the following criteria: (1) Respiratory rate >30/min. (2) Oxygen saturation </=93%. (3) PaO(2)/FiO(2)</=300 mm Hg. (4) Patients, either with shock or respiratory failure, requiring mechanical ventilation, or combined with other organ failure, requiring admission to intensive care unit (ICU). RESULTS: Of 193 patients with severe covid-19, 48 (24.9%) had diabetes. Compared with patients with severe covid-19 without diabetes, patients with diabetes were older, susceptible to receiving mechanical ventilation and admission to ICU, and had higher mortality. In addition, patients with severe covid-19 with diabetes had higher levels of leukocyte count, neutrophil count, high-sensitivity C reaction protein, procalcitonin, ferritin, interleukin (IL) 2 receptor, IL-6, IL-8, tumor necrosis factor alpha, D-dimer, fibrinogen, lactic dehydrogenase and N-terminal pro-brain natriuretic peptide. Among patients with severe covid-19 with diabetes, more non-survivors were men (30 (76.9%) vs 9 (23.1%)). Non-survivors had severe inflammatory response, and cardiac, hepatic, renal and coagulation impairment. Finally, the Kaplan-Meier survival curve showed a trend towards poorer survival in patients with severe covid-19 with diabetes than patients without diabetes. The HR was 1.53 (95% CI 1.02 to 2.30; p=0.041) after adjustment for age, sex, hypertension, cardiovascular disease and cerebrovascular disease by Cox regression. The median survival durations from hospital admission in patients with severe covid-19 with and without diabetes were 10 days and 18 days, respectively. CONCLUSION: The mortality rate in patients with severe covid-19 with diabetes is considerable. Diabetes may lead to an increase in the risk of death. Twit Text FOAVip Clinical characteristics and outcomes of patients with severe covid-19 with diabetes ????BMJ Open Diabetes Res Care http://www.kidney.de/pget.php?&tw=1&pmid=32345579 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32345579 #FOAvip English Wikipedia <ref>{{Cite pmid|32345579}}</ref> Clinical characteristics and outcomes of patients with severe covid-19 with diabetes #MMPMID32345579 Yan Y; Yang Y; Wang F; Ren H; Zhang S; Shi X; Yu X; Dong K BMJ Open Diabetes Res Care 2020[Apr]; 8 (1): ä PMID32345579show ga OBJECTIVE: This study explores the clinical characteristics of patients with diabetes with severe covid-19, and the association of diabetes with survival duration in patients with severe covid-19. RESEARCH DESIGN AND METHODS: In this single-center, retrospective, observational study, the clinical and laboratory characteristics of 193 patients with severe covid-19 were collected. 48 patients with severe covid-19 had diabetes, and 145 patients (ie, the controls) did not have diabetes. A severe case was defined as including at least one of the following criteria: (1) Respiratory rate >30/min. (2) Oxygen saturation |Adult[MESH] |Aged[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |China[MESH] |Coronavirus Infections/*complications/*mortality[MESH] |Diabetes Mellitus/*virology[MESH] |Female[MESH] |Humans[MESH] |Inflammation[MESH] |Kaplan-Meier Estimate[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications/*mortality[MESH] |Respiration, Artificial[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH]Clinical characteristics and outcomes of patients with severe covid-19(epmc).pdf DeepDyve Pubget Overpricing