Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3390/cells9041063 http://scihub22266oqcxt.onion/10.3390/cells9041063 32344698!7226443!32344698     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32344698&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Cells 2020 ; 9 (4): ? Nephropedia Template TP {{tp|p=32344698|t=2020. The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside |pdf=|usr=}}{{32344698}} gab.com Text The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside JO: Cells http://www.kidney.de/pget.php?&tw=1&pmid=32344698 #FOAvip Pancreatic cancer is one of the deadliest cancer types urgently requiring effective therapeutic strategies. Autophagy occurs in several compartments of pancreatic cancer tissue including cancer cells, cancer associated fibroblasts, and immune cells where it can be subjected to a multitude of stimulatory and inhibitory signals fine-tuning its activity. Therefore, the effects of autophagy on pancreatic carcinogenesis and progression differ in a stage and context dependent manner. In the initiation stage autophagy hinders development of preneoplastic lesions; in the progression stage however, autophagy promotes tumor growth. This double-edged action of autophagy makes it a hard therapeutic target. Indeed, autophagy inhibitors have not yet shown survival improvements in clinical trials, indicating a need for better evaluation of existing results and smarter targeting techniques. Clearly, the role of autophagy in pancreatic cancer is complex and many aspects have to be considered when moving from the bench to the bedside. Twit Text FOAVip The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside ????Cells http://www.kidney.de/pget.php?&tw=1&pmid=32344698 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32344698 #FOAvip English Wikipedia <ref>{{Cite pmid|32344698}}</ref> The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside #MMPMID32344698 Gorgulu K; Diakopoulos KN; Kaya-Aksoy E; Ciecielski KJ; Ai J; Lesina M; Algul H Cells 2020[Apr]; 9 (4): ? PMID32344698show ga Pancreatic cancer is one of the deadliest cancer types urgently requiring effective therapeutic strategies. Autophagy occurs in several compartments of pancreatic cancer tissue including cancer cells, cancer associated fibroblasts, and immune cells where it can be subjected to a multitude of stimulatory and inhibitory signals fine-tuning its activity. Therefore, the effects of autophagy on pancreatic carcinogenesis and progression differ in a stage and context dependent manner. In the initiation stage autophagy hinders development of preneoplastic lesions; in the progression stage however, autophagy promotes tumor growth. This double-edged action of autophagy makes it a hard therapeutic target. Indeed, autophagy inhibitors have not yet shown survival improvements in clinical trials, indicating a need for better evaluation of existing results and smarter targeting techniques. Clearly, the role of autophagy in pancreatic cancer is complex and many aspects have to be considered when moving from the bench to the bedside. |*Autophagy[MESH] |*Translational Research, Biomedical[MESH] |Animals[MESH] |Clinical Trials as Topic[MESH] |Humans[MESH] |Molecular Targeted Therapy[MESH] |Pancreatic Neoplasms/*pathology/therapy[MESH]The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bed(epmc).pdf DeepDyve Pubget Overpricing