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10.1016/j.cmi.2020.04.023

http://scihub22266oqcxt.onion/10.1016/j.cmi.2020.04.023
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32344166!7182753!32344166
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suck abstract from ncbi

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  • COVID-19 pandemic-a focused review for clinicians #MMPMID32344166
  • Cevik M; Bamford CGG; Ho A
  • Clin Microbiol Infect 2020[Jul]; 26 (7): 842-847 PMID32344166show ga
  • BACKGROUND: The COVID-19 pandemic caused by SARS-CoV-2 remains a significant issue for global health, economics and society. A wealth of data has been generated since its emergence in December 2019, and it is vital for clinicians to keep up with this data from across the world at a time of uncertainty and constantly evolving guidelines and clinical practice. OBJECTIVES: Here we provide an update for clinicians on the recent developments in the virology, diagnostics, clinical presentation, viral shedding, and treatment options for COVID-19 based on current literature. SOURCES: We considered published peer-reviewed papers and non-peer-reviewed pre-print manuscripts on COVID19 and related aspects with an emphasis on clinical management aspects. CONTENT: We describe the virological characteristics of SARS-CoV-2 and the clinical course of COVID-19 with an emphasis on diagnostic challenges, duration of viral shedding, severity markers and current treatment options. IMPLICATIONS: The key challenge in managing COVID-19 remains patient density. However, accurate diagnosis as well as early identification and management of high-risk severe cases are important for many clinicians. For improved management of cases, there is a need to understand test probability of serology, qRT-PCR and radiological testing, and the efficacy of available treatment options that could be used in severe cases with a high risk of mortality.
  • |Betacoronavirus/genetics/*pathogenicity/physiology[MESH]
  • |Communicable Disease Control/*methods[MESH]
  • |Coronavirus Infections/*diagnosis/epidemiology/*pathology/transmission[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/epidemiology/*pathology/transmission[MESH]
  • |Virus Shedding/physiology[MESH]


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  • suck abstract from ncbi

    842 7.26 2020