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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Head+Neck 2020 ; 42 (6): 1218-1226 Nephropedia Template TP
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Respiratory and pulmonary complications in head and neck cancer patients: Evidence-based review for the COVID-19 era #MMPMID32343013
Silverman DA; Lin C; Tamaki A; Puram SV; Carrau RL; Seim NB; Eskander A; Rocco JW; Old MO; Kang SY
Head Neck 2020[Jun]; 42 (6): 1218-1226 PMID32343013show ga
BACKGROUND: Pulmonary complications and infections frequently affect patients with head and neck squamous cell carcinoma (HNSCC). Common characteristics can predispose these patients to the development of severe respiratory illness, which may be particularly relevant during the 2019 coronavirus disease (COVID-19) pandemic. METHODS: A scoping review was performed to assess the impact of pulmonary comorbidities and adverse respiratory outcomes in HNSCC patients. RESULTS: Advanced age, history of tobacco and alcohol abuse, and cardiopulmonary comorbidities are significant risk factors for the development of adverse respiratory outcomes. Treatment toxicities from radiation or chemoradiation therapy significantly increase these risks. CONCLUSION: Respiratory complications are a frequent cause of morbidity and mortality among HNSCC patients, and the COVID-19 pandemic may disproportionately affect this population. Interventions designed to decrease smoking and alcohol use, improve oral hygiene, and aggressively manage medical comorbidities are important to the long-term management and health of these patients.
|Adult[MESH]
|Age Factors[MESH]
|Aged[MESH]
|Alcohol Drinking/epidemiology[MESH]
|COVID-19[MESH]
|Comorbidity[MESH]
|Coronavirus Infections/*epidemiology[MESH]
|Disease-Free Survival[MESH]
|Female[MESH]
|Head and Neck Neoplasms/diagnosis/*epidemiology/therapy[MESH]