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10.1007/s10096-020-03913-9

http://scihub22266oqcxt.onion/10.1007/s10096-020-03913-9
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32342252!7185831!32342252
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suck abstract from ncbi


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pmid32342252      Eur+J+Clin+Microbiol+Infect+Dis 2020 ; 39 (6): 1059-1061
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  • Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards #MMPMID32342252
  • La Scola B; Le Bideau M; Andreani J; Hoang VT; Grimaldier C; Colson P; Gautret P; Raoult D
  • Eur J Clin Microbiol Infect Dis 2020[Jun]; 39 (6): 1059-1061 PMID32342252show ga
  • In a preliminary clinical study, we observed that the combination of hydroxychloroquine and azithromycin was effective against SARS-CoV-2 by shortening the duration of viral load in Covid-19 patients. It is of paramount importance to define when a treated patient can be considered as no longer contagious. Correlation between successful isolation of virus in cell culture and Ct value of quantitative RT-PCR targeting E gene suggests that patients with Ct above 33-34 using our RT-PCR system are not contagious and thus can be discharged from hospital care or strict confinement for non-hospitalized patients.
  • |*Patient Discharge[MESH]
  • |*Viral Load[MESH]
  • |Animals[MESH]
  • |Betacoronavirus/isolation & purification/*physiology[MESH]
  • |COVID-19[MESH]
  • |Chlorocebus aethiops[MESH]
  • |Coronavirus Infections/*diagnosis/*virology[MESH]
  • |France[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/*virology[MESH]
  • |RNA, Viral/*analysis[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Specimen Handling/standards[MESH]


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