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10.1111/1471-0528.16278

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32339382!7267664!32339382
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suck abstract from ncbi


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pmid32339382      BJOG 2020 ; 127 (9): 1116-1121
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  • Vaginal delivery in SARS-CoV-2-infected pregnant women in Northern Italy: a retrospective analysis #MMPMID32339382
  • Ferrazzi E; Frigerio L; Savasi V; Vergani P; Prefumo F; Barresi S; Bianchi S; Ciriello E; Facchinetti F; Gervasi MT; Iurlaro E; Kustermann A; Mangili G; Mosca F; Patane L; Spazzini D; Spinillo A; Trojano G; Vignali M; Villa A; Zuccotti GV; Parazzini F; Cetin I
  • BJOG 2020[Aug]; 127 (9): 1116-1121 PMID32339382show ga
  • OBJECTIVE: To report mode of delivery and immediate neonatal outcome in women infected with COVID-19. DESIGN: Retrospective study. SETTING: Twelve hospitals in northern Italy. PARTICIPANTS: Pregnant women with COVID-19-confirmed infection who delivered. EXPOSURE: COVID 19 infection in pregnancy. METHODS: SARS-CoV-2-infected women who were admitted and delivered from 1 to 20 March 2020 were eligible. Data were collected from the clinical records using a standardised questionnaire on maternal general characteristics, any medical or obstetric co-morbidity, course of pregnancy, clinical signs and symptoms, treatment of COVID 19 infection, mode of delivery, neonatal data and breastfeeding. MAIN OUTCOME AND MEASURES: Data on mode of delivery and neonatal outcome. RESULTS: In all, 42 women with COVID-19 delivered at the participating centres; 24 (57.1%, 95% CI 41.0-72.3) delivered vaginally. An elective caesarean section was performed in 18/42 (42.9%, 95% CI 27.7-59.0) cases: in eight cases the indication was unrelated to COVID-19 infection. Pneumonia was diagnosed in 19/42 (45.2%, 95% CI 29.8-61.3) cases: of these, 7/19 (36.8%, 95% CI 16.3-61.6) required oxygen support and 4/19 (21.1%, 95% CI 6.1-45.6) were admitted to a critical care unit. Two women with COVID-19 breastfed without a mask because infection was diagnosed in the postpartum period: their newborns tested positive for SARS-Cov-2 infection. In one case, a newborn had a positive test after a vaginal operative delivery. CONCLUSIONS: Although postpartum infection cannot be excluded with 100% certainty, these findings suggest that vaginal delivery is associated with a low risk of intrapartum SARS-Cov-2 transmission to the newborn. TWEETABLE ABSTRACT: This study suggests that vaginal delivery may be associated with a low risk of intrapartum SARS-Cov-2 transmission to the newborn.
  • |*Betacoronavirus[MESH]
  • |*Infectious Disease Transmission, Vertical[MESH]
  • |Adult[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*diagnosis/*transmission[MESH]
  • |Delivery, Obstetric/*adverse effects[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant, Newborn[MESH]
  • |Italy[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/*transmission[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*diagnosis/virology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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