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10.1016/j.ijantimicag.2020.105995 http://scihub22266oqcxt.onion/10.1016/j.ijantimicag.2020.105995 32335281!7180159!32335281     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32335281&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Int+J+Antimicrob+Agents 2020 ; 55 (6): 105995 Nephropedia Template TP {{tp|p=32335281|t=2020. Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19 |pdf=|usr=}}{{32335281}} gab.com Text Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19 JO: Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32335281 #FOAvip Coronavirus disease 2019 (COVID-19) caused by the previously unknown pathogen, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is now a global pandemic. There are no vaccines or specific treatments against this new virus; therefore, there is an urgent need to advance novel therapeutic interventions for COVID-19. Glycyrrhizin is a triterpene saponin with various biological functions and pharmacological effects. This brief article discusses the therapeutic potential of glycyrrhizin for the treatment of COVID-19 from the perspective of its pharmacological action, including binding angiotensin-converting enzyme II (ACE2), downregulating proinflammatory cytokines, inhibiting the accumulation of intracellular reactive oxygen species (ROS), inhibiting thrombin, inhibiting the hyperproduction of airway exudates, and inducing endogenous interferon. Twit Text FOAVip Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19 ????Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32335281 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32335281 #FOAvip English Wikipedia <ref>{{Cite pmid|32335281}}</ref> Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19 #MMPMID32335281 Luo P; Liu D; Li J Int J Antimicrob Agents 2020[Jun]; 55 (6): 105995 PMID32335281show ga Coronavirus disease 2019 (COVID-19) caused by the previously unknown pathogen, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is now a global pandemic. There are no vaccines or specific treatments against this new virus; therefore, there is an urgent need to advance novel therapeutic interventions for COVID-19. Glycyrrhizin is a triterpene saponin with various biological functions and pharmacological effects. This brief article discusses the therapeutic potential of glycyrrhizin for the treatment of COVID-19 from the perspective of its pharmacological action, including binding angiotensin-converting enzyme II (ACE2), downregulating proinflammatory cytokines, inhibiting the accumulation of intracellular reactive oxygen species (ROS), inhibiting thrombin, inhibiting the hyperproduction of airway exudates, and inducing endogenous interferon. |Angiotensin-Converting Enzyme 2[MESH] |Anti-Inflammatory Agents/*therapeutic use[MESH] |Betacoronavirus/*drug effects[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Coronavirus Infections/*drug therapy[MESH] |Cytokines/blood[MESH] |Glycyrrhizic Acid/*therapeutic use[MESH] |Humans[MESH] |Interferons/biosynthesis/immunology[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/metabolism[MESH] |Pneumonia, Viral/*drug therapy[MESH] |Reactive Oxygen Species/metabolism[MESH] |SARS-CoV-2[MESH] |Virus Attachment/drug effects[MESH]Pharmacological perspective: glycyrrhizin may be an efficacious therap(epmc).pdf DeepDyve Pubget Overpricing