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10.1016/j.chest.2020.04.015

http://scihub22266oqcxt.onion/10.1016/j.chest.2020.04.015
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32335068!7194656!32335068
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suck abstract from ncbi


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pmid32335068      Chest 2020 ; 158 (2): e55-e58
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  • Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock #MMPMID32335068
  • Wang H; Das S; Wieruszewski PM; Taji J; Bartlett B; Azad N; Chowdhury A; Kolar GJ; Jain N; Subla MR; Khan SA
  • Chest 2020[Aug]; 158 (2): e55-e58 PMID32335068show ga
  • We report the case of an 88-year-old man with coronavirus disease 2019 (COVID-19) who presented with ARDS and septic shock. The patient had exquisite BP sensitivity to low-dose angiotensin II (Ang-2), allowing for rapid liberation from high-dose vasopressors. We hypothesize that sensitivity to Ang-2 might be related to biological effect of severe acute respiratory syndrome coronavirus 2 infection. The case is suggestive of a potential role for synthetic Ang-2 for patients with COVID-19 and septic shock. Further studies are needed to confirm our observed clinical efficacy.
  • |Aged, 80 and over[MESH]
  • |Angiotensin II/drug effects/*metabolism[MESH]
  • |Angiotensin-Converting Enzyme Inhibitors/*therapeutic use[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/complications/*drug therapy/metabolism[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/*drug therapy/metabolism[MESH]
  • |Respiratory Distress Syndrome/*drug therapy/etiology[MESH]
  • |SARS-CoV-2[MESH]


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