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Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock #MMPMID32335068
Wang H; Das S; Wieruszewski PM; Taji J; Bartlett B; Azad N; Chowdhury A; Kolar GJ; Jain N; Subla MR; Khan SA
Chest 2020[Aug]; 158 (2): e55-e58 PMID32335068show ga
We report the case of an 88-year-old man with coronavirus disease 2019 (COVID-19) who presented with ARDS and septic shock. The patient had exquisite BP sensitivity to low-dose angiotensin II (Ang-2), allowing for rapid liberation from high-dose vasopressors. We hypothesize that sensitivity to Ang-2 might be related to biological effect of severe acute respiratory syndrome coronavirus 2 infection. The case is suggestive of a potential role for synthetic Ang-2 for patients with COVID-19 and septic shock. Further studies are needed to confirm our observed clinical efficacy.